Somatostatin, a somatotropin release inhibiting factor (SST, SRIF), is a widely distributed
multifunctional cyclic peptide and acts through a transmembrane G protein-coupled receptor …

Somatostatin is an inhibitory neuropeptide, which acts on various targets throughout the
body to regulate a variety of physiological functions including inhibition of endocrine and …

Purpose: The somatostatin (SS) receptor subtype 2 (sst2) is the principal mediator of the
antiproliferative effects of SS and has the highest affinity for the commercially available SS …

Somatostatin receptors are clinically validated GPCR biomarkers for diagnosis and
treatment of various neuroendocrine tumors (NET). Among the five somatostatin receptors …

The somatostatin receptor subtype 2 (SSTR2) was detected in a wide range of human and
rat tumors using in vitro receptor binding ([125 I] MK-678), receptor gene expression …

Background Treatment regimens for patients with metastatic or recurrent post-radiation,
locoregional, unresectable salivary cancer are limited. An inverse correlation between …

Somatostatin (SST) via five Gi coupled receptors namely SSTR1-5 is known to inhibit cell
proliferation by cytostatic and cytotoxic mechanisms. Heterodimerization plays a crucial role …

Somatostatin receptor subtype 2 (SSTR2) is the most frequently expressed SSTR subtype in
normal human tissues. SSTR2 expression is differentially regulated in various tumor types …

Aims To investigate the status of somatostatin receptors (SSTR s) in resected hepatocellular
carcinoma (HCC). Methods and results Transcript and protein levels of SSTR 2, SSTR 3 and …

Head and neck squamous cell carcinomas (HNSCC) constitute a heterogeneous cluster of
tumors celebrated for their predisposition to metastasize and exhibit local recurrence …