BACKGROUND: Somatostatin inhibits cell proliferation through interaction with its cellular
receptor, somatostatin receptors (SSTRs). We have previously demonstrated that …

Somatostatin is known to inhibit the secretion of various hormones by acting on endocrine
cells through the somatostatin receptor 2 (SSTR2). Immunohistochemical evaluation of …

Background and Aims: The somatostatin receptor SST2 mediates the antiproliferative effect
of stable somatostatin analogues. SST2 gene expression is lost in most human pancreatic …

Detection of thymic tumors by [111In-DTPA0] octreotide scintigraphy and the antitumor effect
exerted by somatostatin (SS) analogs suggest significant expression of SS receptors (SSRs) …

Hematological and oncological disorders represent leading causes of childhood mortality.
Neuropeptide somatostatin (SST) has been previously demonstrated in various pediatric …

Colorectal cancer (CRC) is the second most lethal malignancy around the world. Limited
efficacy of immunotherapy creates an urgent need for development of novel treatment …

Somatostatin is a neuropeptide that acts as an endogenous inhibitor of various cellular
functions including endocrine and exocrine secretions and the proliferation of normal and …

Human tumors frequently express somatostatin receptors. However, none of the receptor
subtype proteins have been individually visualized in normal or neoplastic human tissues …

Gliomas are the most prevalent primary malignant central nervous system tumors among all
tumors occurring in the brain and spinal cord. The poor outcome of glioma requires the …

In the present study, we detected the expression of SSTR3 protein in 40 patients with gastric
adenocarcinoma and 40 cases of normal gastric mucosa by immunoperoxidased staining …