Biomedical researchers interested in amyotrophic lateral sclerosis (ALS) must invoke newly
developing technologies if we are to discover pharmaceutical treatments that will help a …

Selective death of upper and lower motor neurons in the motor cortex, brainstem, and spinal
cord is the hallmark of amyotrophic lateral sclerosis (ALS). ALS is a neurodegenerative …

Several mechanisms have been proposed to account for the progressive motor neurone
death evident in amyotrophic lateral sclerosis. These include oxidative stress, neurofilament …

Amyotrophic lateral sclerosis (ALS) is a clinically severe and fatal neurodegenerative
disease characterized by a loss of both upper and lower motor neurons, resulting in …

Amyotrophic lateral sclerosis (ALS) is an unrelenting progressive neurodegenerative
disease causing progressive weakness, ultimately leading to death. Despite aggressive …

Amyotrophic lateral sclerosis (ALS) or Lou Gehrig's disease is the most common motor
neuron disease in human adults, described as early as 1869 by a French neurobiologist and …

Introduction: Amyotrophic lateral sclerosis (ALS) is one of the most devastating neurological
disorders, affecting approximately half a million people worldwide. Currently there is no cure …

Introduction: Amyotrophic lateral sclerosis (ALS) is a devastating illness of unclear etiology
affecting motor neurons. It causes unremitting muscle paralysis, atrophy and death usually …

Amyotrophic lateral sclerosis (ALS), identified as a distinct clinical entity by Charcot since the
end of the nineteenth century, is a devastating and fatal neurodegenerative disorder that …

Since its first description by Charcot over 120 years ago, amyotrophic lateral sclerosis (ALS)
has remained an enigmatic disease. However, significant advances have been made during …