Identifying the mechanisms by which air pollution causes human health effects is a daunting
task. Airsheds around the world are composed of pollution mixtures made up of hundreds of …

Exposure to particulate matter (PM) is consistently associated with increased morbidity and
mortality rate. The mechanisms for these adverse health effects have been vigorously …

Context: Exposure to ambient particulate air pollution is associated with increased
cardiovascular and respiratory morbidity and mortality. It is necessary to understand causal …

In vitro models mimicking the human respiratory system are essential when investigating the
toxicological effects of inhaled indoor air particulate matter (PM). We present a pulmonary …

When one considers the cellular heterogeneity of the normal lung, it is reasonable to
recognize that the response of the lung to toxicant-induced injury and the subsequent repair …

Particulate matter (PM) is one of the most relevant environment-related health issues all over
the world since high concentrations of this pollutant are registered in cities from all the …

We have studied the responses of a target cell model to culture medium conditioned by lung
macrophages exposed to ambient airborne particulate matter. Macrophages were harvested …

Comprehensive and systematic approaches are needed to understand the molecular basis
for the health effects of particulate matter (PM) reported in epidemiological studies. Due to …

Urban air pollution represents a major problem affecting millions of people around the world.
It has been considered by the World Health Organization (WHO) as responsible for 865,000 …

Currently, the biological mechanisms controlling adverse reactions to particulate matter are
uncertain, but are likely to include oxidative lung injury, inflammation, infection, and …