Assessing the role of particulate matter size and composition on gene expression in pulmonary cells
DW Graff, MT Schmitt, LA Dailey, RM Duvall… - Inhalation …, 2007 - Taylor & Francis
Identifying the mechanisms by which air pollution causes human health effects is a daunting
task. Airsheds around the world are composed of pollution mixtures made up of hundreds of …
task. Airsheds around the world are composed of pollution mixtures made up of hundreds of …
The role of in vitro gene expression profiling in particulate matter health research
YCT Huang - Journal of Toxicology and Environmental Health, Part …, 2013 - Taylor & Francis
Exposure to particulate matter (PM) is consistently associated with increased morbidity and
mortality rate. The mechanisms for these adverse health effects have been vigorously …
mortality rate. The mechanisms for these adverse health effects have been vigorously …
Gene and protein responses of human lung tissue explants exposed to ambient particulate matter of different sizes
B Hoogendoorn, K Berube, C Gregory, T Jones… - Inhalation …, 2012 - Taylor & Francis
Context: Exposure to ambient particulate air pollution is associated with increased
cardiovascular and respiratory morbidity and mortality. It is necessary to understand causal …
cardiovascular and respiratory morbidity and mortality. It is necessary to understand causal …
Human airway construct model is suitable for studying transcriptome changes associated with indoor air particulate matter toxicity
In vitro models mimicking the human respiratory system are essential when investigating the
toxicological effects of inhaled indoor air particulate matter (PM). We present a pulmonary …
toxicological effects of inhaled indoor air particulate matter (PM). We present a pulmonary …
Alterations in gene expression in pulmonary cells following particle interactions
JN Finkelstein, EG Barrett - LUNG BIOLOGY IN HEALTH AND …, 2000 - api.taylorfrancis.com
When one considers the cellular heterogeneity of the normal lung, it is reasonable to
recognize that the response of the lung to toxicant-induced injury and the subsequent repair …
recognize that the response of the lung to toxicant-induced injury and the subsequent repair …
Particulate matter physico-chemical characterization and in vitro toxicological effects
M Gualtieri, F Ledoux, A Verdin, S Billet… - … : Origin, emissions and …, 2017 - boa.unimib.it
Particulate matter (PM) is one of the most relevant environment-related health issues all over
the world since high concentrations of this pollutant are registered in cities from all the …
the world since high concentrations of this pollutant are registered in cities from all the …
Sequential in vitro effects of airborne particles in lung macrophages and reporter CAT-gene cell lines
P Goegan, R Vincent, P Kumarathasan, J Brook - Toxicology in vitro, 1998 - infona.pl
We have studied the responses of a target cell model to culture medium conditioned by lung
macrophages exposed to ambient airborne particulate matter. Macrophages were harvested …
macrophages exposed to ambient airborne particulate matter. Macrophages were harvested …
Altered gene expression profiles of rat lung in response to an emission particulate and its metal constituents
SS Nadadur, UP Kodavanti - Journal of toxicology and …, 2002 - Taylor & Francis
Comprehensive and systematic approaches are needed to understand the molecular basis
for the health effects of particulate matter (PM) reported in epidemiological studies. Due to …
for the health effects of particulate matter (PM) reported in epidemiological studies. Due to …
Cellular mechanisms behind particulate matter air pollution related health effects
E Alfaro-Moreno, C García-Cuellar… - Air Pollution: Health …, 2010 - api.taylorfrancis.com
Urban air pollution represents a major problem affecting millions of people around the world.
It has been considered by the World Health Organization (WHO) as responsible for 865,000 …
It has been considered by the World Health Organization (WHO) as responsible for 865,000 …
Functional genomics of particle-induced lung injury
GD Leikauf, SA McDowell, K Gammon… - Inhalation …, 2000 - Taylor & Francis
Currently, the biological mechanisms controlling adverse reactions to particulate matter are
uncertain, but are likely to include oxidative lung injury, inflammation, infection, and …
uncertain, but are likely to include oxidative lung injury, inflammation, infection, and …
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