Neuroendocrine tumor biomarkers: current status and perspectives

IM Modlin, K Oberg, A Taylor, I Drozdov, L Bodei… - …, 2015 - karger.com
The identification of accurate harbingers of disease status and therapeutic efficacy are
critical requirements in precise diagnosis and effective management. Initially, tissue analysis …

Neuroendocrine tumor biomarkers: From monoanalytes to transcripts and algorithms

IM Modlin, L Bodei, M Kidd - … practice & research Clinical endocrinology & …, 2016 - Elsevier
The management of neuroendocrine neoplasia remains a perplexing problem because of
the lack of knowledge of the biology of the disease, its late presentation, the relative …

Circulating neuroendocrine tumor biomarkers: past, present and future

P Komarnicki, J Musiałkiewicz, A Stańska… - Journal of Clinical …, 2022 - mdpi.com
Neuroendocrine tumors are a heterogeneous group of neoplasms originating from the
diffuse endocrine system. Depending on primary location and hormonal status, they range in …

An overview of circulating biomarkers in neuroendocrine neoplasms: a clinical guide

M Bevere, F Masetto, ME Carazzolo, A Bettega… - Diagnostics, 2023 - mdpi.com
Neuroendocrine neoplasms (NENs) are a heterogeneous group of diseases that are
characterized by different behavior and clinical manifestations. The diagnosis and …

The Quest for Circulating Biomarkers in Neuroendocrine Neoplasms: a Clinical Perspective

L Mariën, O Islam, S Chhajlani, W Lybaert… - … Treatment Options in …, 2023 - Springer
Opinion statement Given the considerable heterogeneity in neuroendocrine neoplasms
(NENs), it appears unlikely that a sole biomarker exists capable of fully capturing all useful …

Neuroendocrine tumor markers

SWJ Lamberts, LJ Hofland, FRE Nobels - Frontiers in neuroendocrinology, 2001 - Elsevier
Tumor markers used in the diagnosis and follow-up of patients with neuroendocrine tumors
are in most instances not specific for a given tumor and circulate under normal conditions in …

Consensus on biomarkers for neuroendocrine tumour disease

K Oberg, IM Modlin, W De Herder, M Pavel… - The Lancet …, 2015 - thelancet.com
Management of neuroendocrine neoplasia represents a clinical challenge because of its
late presentation, lack of treatment options, and limitations in present imaging modalities …

Role of biomarker tests for diagnosis of neuroendocrine tumours

J Hofland, WT Zandee, WW de Herder - Nature Reviews Endocrinology, 2018 - nature.com
Neuroendocrine tumours (NETs) are neoplasms that arise from neuroendocrine cells.
Neuroendocrine cells and their tumours can secrete a wide range of amines and …

Second-generation neuroendocrine immunohistochemical markers: reflections from clinical implementation

CC Juhlin - Biology, 2021 - mdpi.com
Simple Summary Neuroendocrine tumors are a collection of neoplastic lesions arising in
cells with traits similar to hormone-producing and nerve cells with the ability to secrete …

Utility of a ready-to-use PCR system for neuroendocrine tumor diagnosis

M Kidd, IA Drozdov, S Matar, N Gurunlian, NJ Ferranti… - PLoS …, 2019 - journals.plos.org
Background Multigene-based PCR tests are time-consuming and limiting aspects of the
protocol include increased risk of operator-based variation. In addition, such protocols are …