Zinc (Zn) is one of the most important trace elements in the human body and plays a key role
in various physiological processes, especially in bone metabolism. Zn-containing materials …

Bone fractures and critical-size bone defects are significant public health issues, and clinical
treatment outcomes are closely related to the intrinsic properties of the utilized implant …

Zinc has been described as the 'calcium of the twenty-first century'. Zinc-based degradable
biomaterials have recently emerged thanks to their intrinsic physiological relevance …

Introduction To repair bone defects, a variety of bone substitution materials have been used,
such as ceramics, metals, natural and synthetic polymers, and combinations thereof. In …

Large-sized bone defects are a great challenge in clinics and considerably impair the quality
of patients' daily life. Tissue engineering strategies using cells, scaffolds, and bioactive …

Zinc is an essential mineral that is required for normal skeletal growth and bone
homeostasis. Furthermore, zinc appears to be able to promote bone regeneration. However …

Introduction Using the alternative compounds, such as ceramics, metals, natural and
synthetic polymers, and their combination was mentioned for the bone regeneration. Many …

While bone tissue is known for its inherent regenerative abilities, various pathological
conditions and trauma can disrupt its meticulously regulated processes of bone formation …

Bone defects are commonly caused by severe trauma, malignant tumors, or congenital
diseases and remain among the toughest clinical problems faced by orthopedic surgeons …

Zn-based alloys are promising biodegradable implants for bone defect repair due to their
good mechanical performance and degradability. However, local Zn2+ released from Zn …