Circulating concentrations of" free" leptin in relation to fat mass and appetite in gastrointestinal cancer patients

AM Wallace, A Kelly, N Sattar, CS McArdle… - Nutrition and …, 2002 - Taylor & Francis
Recent studies have suggested that circulating concentrations of leptin might play a role in
cancer cachexia. In the first part of the study, we compared circulating concentrations of free …

Effect of weight loss and the inflammatory response on leptin concentrations in gastrointestinal cancer patients.

AM Wallace, N Sattar, DC McMillan - … cancer research: an official journal of …, 1998 - AACR
Animal research suggests that leptin may have an important role in the regulation of energy
balance. The role of leptin in the progressive involuntary weight loss associated with cancer …

Serum values of proinflammatory cytokines are inversely correlated with serum leptin levels in patients with advanced stage cancer at different sites

G Mantovani, A Macciò, C Madeddu, L Mura… - Journal of molecular …, 2001 - Springer
Leptin is a recently identified hormone produced by the adipocyte ob gene which acts as a
negative feedback signal critical to the normal control of food intake and body weight. A …

A longitudinal study of leptin and appetite, resting energy expenditure and body fat mass in weight-stable cancer patients

R Maguire, DC McMillan, AM Wallace, C McArdle - Cytokine, 2002 - Elsevier
Leptin and its relationship with energy metabolism in male weight-stable patients with
colorectal liver metastases (n= 14) was assessed at baseline and after 6 weeks. At baseline …

Serum levels of leptin and proinflammatory cytokines in patients with advanced-stage cancer at different sites

G Mantovani, A Macciò, L Mura, E Massa… - Journal of Molecular …, 2000 - Springer
Leptin is a recently identified hormone produced by the adipocyte ob gene which acts as a
negative feedback signal critical to the normal control of food intake and body weight. A …

Plasma concentration of total leptin and human lung-cancer-associated cachexia

JPFHA Simons, AMWJ Schols, LA Campfield… - Clinical …, 1997 - portlandpress.com
1. Adipocyte-derived leptin is postulated to represent the afferent hormonal signal to the
hypothalamus in a feedback mechanism that regulates fat mass. In this proposed feedback …

Serum leptin concentration and advanced gastrointestinal cancers: a case controlled study

FF Bolukbas, H Kilic, C Bolukbas, M Gumus, M Horoz… - BMC cancer, 2004 - Springer
Background Serum leptin level is associated with appetite and energy expenditure in
healthy individuals. We aimed to evaluate the serum leptin concentration and the other …

Low serum leptin level in colon cancer patients without significant weight loss

F Arpaci, MI Yilmaz, A Ozet, H Ayta, B Ozturk… - Tumori …, 2002 - journals.sagepub.com
Aims and Background Leptin is a protein that affects the metabolic, neuroendocrine,
reproductive and hematopoietic systems and is involved in the regulation of body weight …

Leptin and its receptors in obese patients with colorectal cancer.

M Stachowicz, U Mazurek… - Journal of Biological …, 2010 - europepmc.org
The purpose of this study is to examine serum concentration of leptin and that of the soluble
form, the Ob-Re receptor, in patients with colorectal cancer, as well as to examine the level …

Serum levels of leptin and proinflammatory cytokines in patients with gastrointestinal cancer

H Dülger, S Alici, MR Ş ekeroǦlu… - … journal of clinical …, 2004 - Wiley Online Library
The aim was to investigate the serum levels of leptin, TNF‐alpha, IL‐1 beta, IL‐6, insulin,
and growth hormone in patients with upper gastrointestinal cancer and cachexia. A total of …