Patients diagnosed with epithelial ovarian cancer (OC) have a 5-year survival rate of 49%.
For early-stage disease, the 5-year survival rate is above 90%. However, advanced-stage …

Simple Summary There are limited non-invasive methods for detecting epithelial ovarian
cancer despite early detection and treatment dramatically increasing survival. As alterations …

Background Despite a myriad of attempts in the last three decades to diagnose ovarian
cancer (OC) earlier, this clinical aim still remains a significant challenge. Aberrant …

Objective Aberrant DNA methylation is an early event in carcinogenesis which could be
leveraged to detect ovarian cancer (OC) in plasma. Methods DNA from frozen OC tissues …

Background Ovarian cancer (OC) is a highly lethal gynecologic cancer, and it is hard to
diagnose at an early stage. Clinically, there are no ovarian cancer-specific markers for early …

OBJECTIVE: Epithelial ovarian carcinoma (OvCa) is rarely detected early, and it is also
difficult to determine whether an adnexal mass is benign or malignant. Previously, we noted …

Ovarian cancer (OC) causes significant morbidity and mortality as neither detection nor
screening of OC is currently feasible at an early stage. Difficulty to promptly diagnose OC in …

Background The identification of sensitive biomarkers for the detection of ovarian cancer is
of high clinical relevance for early detection and/or monitoring of disease recurrence. We …

Breast, ovarian and endometrial cancers cause significant morbidity and mortality. Despite
the presence of existing screening, diagnostic and treatment modalities, they continue to …

OBJECTIVE: Epithelial ovarian cancer (EOC) remains the most lethal disease among
gynecological malignancies. Prompt diagnosis is challenging because of the non-specific …