Overexpression of MicroRNA‐16 Alleviates Atherosclerosis by Inhibition of Inflammatory Pathways

M Wang, J Li, J Cai, L Cheng, X Wang… - BioMed Research …, 2020 - Wiley Online Library
Background. Our previous study demonstrated that the expression of miR‐16 was
downregulated in the cell and animal models of atherosclerosis (AS), a main contributor to …

[HTML][HTML] Regulation of microRNA-155 in atherosclerotic inflammatory responses by targeting MAP3K10

J Zhu, T Chen, L Yang, Z Li, MM Wong, X Zheng… - PloS one, 2012 - journals.plos.org
Aims Accumulating evidence suggest that numerous microRNAs (miRNAs) play important
roles in cell proliferation, apoptosis, and differentiation, as well as various diseases that …

[HTML][HTML] miR‑98 inhibits cell proliferation and induces cell apoptosis by targeting MAPK6 in HUVECs

C Hu, S Huang, F Wu, H Ding - Experimental and …, 2018 - spandidos-publications.com
The aim of current study was to explore the role of microRNA (miR)‑98 in atherosclerosis.
Human vascular endothelial cells (HVECs) were isolated from the peripheral blood of …

[HTML][HTML] MicroRNA-124 inhibits macrophage cell apoptosis via targeting p38/MAPK signaling pathway in atherosclerosis development

X Liang, L Wang, M Wang, Z Liu, X Liu, B Zhang… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
The objective of this study is to characterize the function of microRNA (miR)-124 in the
process of coronary artery disease (CAD). Eighty patients, including 40 CAD patients and 40 …

MicroRNA‐30‐3p suppresses inflammatory factor‐induced endothelial cell injury by targeting TCF21

Z Zhou, Y Chen, D Zhang, S Wu, T Liu… - Mediators of …, 2019 - Wiley Online Library
Atherosclerosis is one of the leading causes of mortality worldwide. Growing evidence
suggested that miRNAs contributed to the progression of atherosclerosis. miR‐30‐5p was …

[HTML][HTML] MicroRNA-497 induces apoptosis and suppresses proliferation via the Bcl-2/Bax-caspase9-caspase3 pathway and cyclin D2 protein in HUVECs

R Wu, S Tang, M Wang, X Xu, C Yao, S Wang - PLoS One, 2016 - journals.plos.org
Introduction MicroRNAs play crucial roles in various types of diseases. However, to date, no
information about the role of miR-497 in the development of atherosclerosis has been …

[HTML][HTML] MicroRNA-186-5p serves as a diagnostic biomarker in atherosclerosis and regulates vascular smooth muscle cell proliferation and migration

B Sun, Q Cao, M Meng, X Wang - Cellular & Molecular Biology Letters, 2020 - Springer
Objective MicroRNA dysregulation occurs in many human diseases, including
atherosclerosis. Here, we examined the serum expression and clinical significance of miR …

MicroRNA-21 deficiency attenuated atherogenesis and decreased macrophage infiltration by targeting Dusp-8

L Gao, H Zeng, T Zhang, C Mao, Y Wang, Z Han… - Atherosclerosis, 2019 - Elsevier
Background and aims Atherosclerosis is a chronic inflammatory disorder mediated by
macrophage activation. MicroRNA-21 (miR-21) is a key regulator in the macrophage …

[HTML][HTML] Microrna-145 accelerates the inflammatory reaction through activation of NF-κB signaling in atherosclerosis cells and mice

S Li, W Sun, H Zheng, F Tian - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Atherosclerosis (AS) is a chronic inflammation, which is a major cause of morbidity and
mortality in the world. Accumulative evidences have demonstrated that miRNAs exert crucial …

Effect of miR-663 on atherosclerosis by regulating the proliferation of vascular smooth muscle cells in lipid plaques

Z Deng, L Li - Vascular, 2023 - journals.sagepub.com
Objectives Atherosclerosis (AS) is the main cause of coronary heart disease, cerebral
infarction, and peripheral vascular disease. microRNAs (miRNAs) are widely distributed in …