Abstract Background: Detecting plasmid-mediated AmpC (pAmpC) β-lactamase-producing
organism is important for optimal infection control and providing accurate and effective …

Objective: The aim of the study was to investigate the occurrence of AmpC-type β-lactamase
producers isolated from two hospitals in Tripoli, Libya. Methods: All clinical isolates (76 K …

Background: AmpC β-lactamase confers resistance to a variety of β-lactam agents, and all
plasmid-mediated AmpC genes are considered clinically significant. The transfer of the …

Plasmid-mediated AmpC beta-lactamases (pAmpCs) are cephalosporinases that hydrolyze
cephamycins as well as other extended-spectrum cephalosporins and are poorly inhibited …

One of the mechanisms of Klebsiella pneumoniae and Escherichia coli resistance to β-
lactam antibiotics is the production of β-lactamase enzymes. Among these are the AmpC β …

Therapeutic options for infections caused by gram-negative organisms expressing plasmid-
mediated AmpC β-lactamases are limited because these organisms are usually resistant to …

Aims: The aim of this study was to characterize pAmpC β-lactamase producing
extraintestinal E. coli, their phylogenetic distribution, resistance pattern, treatment options …

The aim of the present study was to investigate the phenotype and genotype of plasmid‑
mediated AmpC (pAmpC) β‑lactamase in Klebsiella pneumoniae and its antibiotic …

Methods: One hundred consecutive, non-duplicate clinical isolates of K. pneumoniae
collected over a period of one year (June 2008-June 2009) were included in the study. An …

Methods: A total of 241 nosocomial isolates of K. pneumoniae (n= 109) and E. coli (n= 132)
from six geographically distant hospitals in India were included. These were screened for …