Actin dynamics modulate mechanosensitive immobilization of E-cadherin at adherens junctions
W Engl, B Arasi, LL Yap, JP Thiery, V Viasnoff - Nature cell biology, 2014 - nature.com
Mechanical stress is increasingly being shown to be a potent modulator of cell–cell
junctional morphologies in developmental and homeostatic processes. Intercellular force …
junctional morphologies in developmental and homeostatic processes. Intercellular force …
Transmission of cytokinesis forces via E-cadherin dilution and actomyosin flows
During epithelial cytokinesis, the remodelling of adhesive cell–cell contacts between the
dividing cell and its neighbours has profound implications for the integrity, arrangement and …
dividing cell and its neighbours has profound implications for the integrity, arrangement and …
Distinct contributions of tensile and shear stress on E-cadherin levels during morphogenesis
During epithelial morphogenesis, cell contacts (junctions) are constantly remodeled by
mechanical forces that work against adhesive forces. E-cadherin complexes play a pivotal …
mechanical forces that work against adhesive forces. E-cadherin complexes play a pivotal …
E-cadherin junctions as active mechanical integrators in tissue dynamics
During epithelial morphogenesis, E-cadherin adhesive junctions play an important part in
mechanically coupling the contractile cortices of cells together, thereby distributing the …
mechanically coupling the contractile cortices of cells together, thereby distributing the …
Mechanosensitive Adaptation of E-Cadherin Turnover across adherens Junctions
In the natural and technological world, multi-agent systems strongly depend on how the
interactions are ruled between their individual components, and the proper control of time …
interactions are ruled between their individual components, and the proper control of time …
E-cadherin-mediated force transduction signals regulate global cell mechanics
This report elucidates an E-cadherin-based force-transduction pathway that triggers
changes in cell mechanics through a mechanism requiring epidermal growth factor receptor …
changes in cell mechanics through a mechanism requiring epidermal growth factor receptor …
Active tension: the role of cadherin adhesion and signaling in generating junctional contractility
In this chapter, we discuss the cell biology of contractility at cell–cell junctions. As discussed
elsewhere in this volume, contractile forces play key roles in development and tissue …
elsewhere in this volume, contractile forces play key roles in development and tissue …
Stable force balance between epithelial cells arises from F-actin turnover
The propagation of force in epithelial tissues requires that the contractile cytoskeletal
machinery be stably connected between cells through E-cadherin-containing adherens …
machinery be stably connected between cells through E-cadherin-containing adherens …
Cortical F-actin stabilization generates apical–lateral patterns of junctional contractility that integrate cells into epithelia
E-cadherin cell–cell junctions couple the contractile cortices of epithelial cells together,
generating tension within junctions that influences tissue organization. Although junctional …
generating tension within junctions that influences tissue organization. Although junctional …
Neighborly relations: cadherins and mechanotransduction
Cell–cell adhesions are sites where cells experience and resist tugging forces. It has long
been postulated, but not directly tested, that cadherin adhesion molecules may serve in …
been postulated, but not directly tested, that cadherin adhesion molecules may serve in …