Multi-parametric hydrogels support 3D in vitro bioengineered microenvironment models of tumour angiogenesis
Tumour microenvironment greatly influences the development and metastasis of cancer
progression. The development of three dimensional (3D) culture models which mimic that …
progression. The development of three dimensional (3D) culture models which mimic that …
[HTML][HTML] Engineered 3D hydrogels with full-length fibronectin that sequester and present growth factors
Extracellular matrix (ECM)-derived matrices such as Matrigel are used to culture numerous
cell types in vitro as they recapitulate ECM properties that support cell growth, organisation …
cell types in vitro as they recapitulate ECM properties that support cell growth, organisation …
Tunable collagen I hydrogels for engineered physiological tissue micro-environments
EE Antoine, PP Vlachos, MN Rylander - PloS one, 2015 - journals.plos.org
Collagen I hydrogels are commonly used to mimic the extracellular matrix (ECM) for tissue
engineering applications. However, the ability to design collagen I hydrogels similar to the …
engineering applications. However, the ability to design collagen I hydrogels similar to the …
The effect of matrix characteristics on fibroblast proliferation in 3D gels
Engineering synthetic hydrogels on a molecular basis to introduce natural features that are
important in instructing cell behavior is becoming increasingly crucial in biomaterial-based …
important in instructing cell behavior is becoming increasingly crucial in biomaterial-based …
Chemical strategies to engineer hydrogels for cell culture
Two-dimensional and three-dimensional cell culture systems are widely used for biological
studies, and are the basis of the organoid, tissue engineering and organ-on-chip research …
studies, and are the basis of the organoid, tissue engineering and organ-on-chip research …
Independently tuning the biochemical and mechanical properties of 3D hyaluronan-based hydrogels with oxime and Diels–Alder chemistry to culture breast cancer …
For native breast cancer cell growth to be mimicked in vitro as spheroids, a well-defined
matrix that mimics the tumor microenvironment is required. Finding a biomimetic material for …
matrix that mimics the tumor microenvironment is required. Finding a biomimetic material for …
Recreating the tumor microenvironment in a bilayer, hyaluronic acid hydrogel construct for the growth of prostate cancer spheroids
Cancer cells cultured in physiologically relevant, three-dimensional (3D) matrices can
recapture many essential features of native tumor tissues. In this study, a hyaluronic acid …
recapture many essential features of native tumor tissues. In this study, a hyaluronic acid …
Three-dimensional tissue fabrication
VL Tsang, SN Bhatia - Advanced drug delivery reviews, 2004 - Elsevier
In recent years, advances in fabrication technologies have brought a new dimension to the
field of tissue engineering. Using manufacturing-based methods and hydrogel chemistries …
field of tissue engineering. Using manufacturing-based methods and hydrogel chemistries …
3D extracellular matrix interactions modulate tumour cell growth, invasion and angiogenesis in engineered tumour microenvironments
AV Taubenberger, LJ Bray, B Haller, A Shaposhnykov… - Acta biomaterialia, 2016 - Elsevier
Interactions between tumour cells and extracellular matrix proteins of the tumour
microenvironment play crucial roles in cancer progression. So far, however, there are only a …
microenvironment play crucial roles in cancer progression. So far, however, there are only a …
25th anniversary article: engineering hydrogels for biofabrication
With advances in tissue engineering, the possibility of regenerating injured tissue or failing
organs has become a realistic prospect for the first time in medical history. Tissue …
organs has become a realistic prospect for the first time in medical history. Tissue …