Angiogenesis–osteogenesis coupling processes are vital in bone tissue engineering.
Normal biomaterials implanted in bone defects have issues in the sufficient formation of …

Angiogenesis marks the transformation of a benign local tumor into a life‐threatening
disease. Many in vitro assays are available on two‐dimensional (2D) platforms, however …

Conventional in vitro cancer models do not accurately reproduce the tumor
microenvironment (TME), so three-dimensional (3D)-bioprinting represents an excellent tool …

Engineering new tissues utilizing cell transplantation on biodegradable polymer matrices is
an attractive approach to treat patients suffering from the loss or dysfunction of a number of …

One of the continued challenges in engineering clinically applicable tissues is the
establishment of vascularization upon implantation in vivo. Although the effectiveness of an …

Abstract Three-dimensional (3D) tissue-engineered tumor models have the potential to
bridge the gap between monolayer cultures and patient-derived xenografts for the testing of …

Achieving cell spreading and proliferation inside hydrogels that are compatible with
microencapsulation technology represents a major challenge for tissue engineering …

In the three-dimensional (3D) tumor microenvironment, matrix stiffness is associated with the
regulation of tumor cells behaviors. In vitro tumor models with appropriate matrix stiffness …

Abstract Three-dimensional (3D) in vitro tumor spheroids are becoming popular as pre-
clinical platforms for testing the performance of existing drugs or for discovery of innovative …

The complexity and diversity of the biochemical processes that occur during tumorigenesis
and metastasis are frequently over-simplified in the traditional in vitro cell cultures. Two …