Chronic cerebrospinal venous insufficiency and multiple sclerosis

O Khan, M Filippi, MS Freedman, F Barkhof… - Annals of …, 2010 - Wiley Online Library
A chronic state of impaired venous drainage from the central nervous system, termed
chronic cerebrospinal venous insufficiency (CCSVI), is claimed to be a pathologic …

Chronic cerebrospinal venous insufficiency in multiple sclerosis: diagnostic, pathogenetic, clinical and treatment perspectives

R Zivadinov, M Ramanathan, K Dolic… - Expert review of …, 2011 - Taylor & Francis
Chronic cerebrospinal venous insufficiency (CCSVI) was recently described in multiple
sclerosis patients. CCSVI is characterized by impaired brain venous drainage due to outflow …

Endovascular treatment for chronic cerebrospinal venous insufficiency: is the procedure safe?

T Ludyga, M Kazibudzki, M Simka, M Hartel… - …, 2010 - journals.sagepub.com
Objectives The aim of this report is to assess the safety of endovascular treatment for chronic
cerebrospinal venous insufficiency (CCSVI). Although balloon angioplasty and stenting …

Safety profile of endovascular treatment for chronic cerebrospinal venous insufficiency in patients with multiple sclerosis

I Petrov, L Grozdinski, G Kaninski… - Journal of …, 2011 - journals.sagepub.com
Purpose To evaluate the safety of endovascular treatment of chronic cerebrovascular
insufficiency (CCSVI) in patients with multiple sclerosis (MS). Methods In a 1-year period …

What went wrong? The flawed concept of cerebrospinal venous insufficiency

JM Valdueza, F Doepp, SJ Schreiber… - Journal of Cerebral …, 2013 - journals.sagepub.com
In 2006, Zamboni reintroduced the concept that chronic impaired venous outflow of the
central nervous system is associated with multiple sclerosis (MS), coining the term of chronic …

Proposed chronic cerebrospinal venous insufficiency criteria do not predict multiple sclerosis risk or severity

D Centonze, R Floris, M Stefanini, S Rossi… - Annals of …, 2011 - Wiley Online Library
Objective: It is still unclear whether chronic cerebrospinal venous insufficiency (CCSVI) is
associated with multiple sclerosis (MS), because substantial methodological differences …

Safety of endovascular treatment of chronic cerebrospinal venous insufficiency: a report of 240 patients with multiple sclerosis

KD Mandato, PF Hegener, GP Siskin, ZJ Haskal… - Journal of Vascular and …, 2012 - Elsevier
PURPOSE: To evaluate the safety of outpatient endovascular treatment in patients with
multiple sclerosis (MS) and chronic cerebrospinal venous insufficiency (CCSVI) …

[HTML][HTML] A prospective open-label study of endovascular treatment of chronic cerebrospinal venous insufficiency

P Zamboni, R Galeotti, E Menegatti… - Journal of vascular …, 2009 - Elsevier
OBJECTIVE: Chronic cerebrospinal venous insufficiency (CCSVI) is characterized by
combined stenoses of the principal pathways of extracranial venous drainage, including the …

Complications in MS patients after CCSVI procedures abroad (Calgary, AB)

JM Burton, K Alikhani, M Goyal, F Costello… - Canadian journal of …, 2011 - cambridge.org
Background: The “chronic cerebrospinal venous insufficiency” or “CCSVI” hypothesis,
namely that multiple sclerosis (MS) is caused by abnormalities in the azygous and internal …

Efficacy and safety of extracranial vein angioplasty in multiple sclerosis: a randomized clinical trial

P Zamboni, L Tesio, S Galimberti, L Massacesi… - JAMA …, 2018 - jamanetwork.com
Importance Chronic cerebrospinal venous insufficiency (CCSVI) is characterized by
restricted venous outflow from the brain and spinal cord. Whether this condition is …