A role for the cortex in sleep–wake regulation
Cortical and subcortical circuitry are thought to play distinct roles in the generation of sleep
oscillations and global state control, respectively. Here we silenced a subset of neocortical …
oscillations and global state control, respectively. Here we silenced a subset of neocortical …
A neural circuit for circadian regulation of arousal
An unknown aspect of behavioral state regulation is how the circadian oscillator of the
suprachiasmatic nucleus (SCN) regulates sleep and waking. In this report, we describe the …
suprachiasmatic nucleus (SCN) regulates sleep and waking. In this report, we describe the …
The claustrum coordinates cortical slow-wave activity
K Narikiyo, R Mizuguchi, A Ajima, M Shiozaki… - Nature …, 2020 - nature.com
During sleep and awake rest, the neocortex generates large-scale slow-wave (SW) activity.
Here, we report that the claustrum coordinates neocortical SW generation. We established a …
Here, we report that the claustrum coordinates neocortical SW generation. We established a …
Local sleep and learning
Human sleep is a global state whose functions remain unclear. During much of sleep,
cortical neurons undergo slow oscillations in membrane potential, which appear in …
cortical neurons undergo slow oscillations in membrane potential, which appear in …
[HTML][HTML] Sleep-stage-specific regulation of cortical excitation and inhibition
Sleep is characterized by unique patterns of cortical activity alternating between the stages
of slow-wave sleep (SWS) and rapid-eye movement (REM) sleep. How these patterns relate …
of slow-wave sleep (SWS) and rapid-eye movement (REM) sleep. How these patterns relate …
Back to baseline: sleep recalibrates synapses
N Niethard, J Born - Nature Neuroscience, 2019 - nature.com
In 2008, Vyazovskiy et al. published a seminal study demonstrating that sleep induces a
widespread downscaling of synapses that counters the synaptic upscaling that occurred …
widespread downscaling of synapses that counters the synaptic upscaling that occurred …
Sleep-wake neurobiology
G Vanini, P Torterolo - … and Sleep: Molecular, Functional and Clinical …, 2021 - Springer
Sleep and wakefulness are complex, tightly regulated behaviors that occur in virtually all
animals. With recent exciting developments in neuroscience methodologies such as …
animals. With recent exciting developments in neuroscience methodologies such as …
[HTML][HTML] In vitro cortical network firing is homeostatically regulated: a model for sleep regulation
Prolonged wakefulness leads to a homeostatic response manifested in increased amplitude
and number of electroencephalogram (EEG) slow waves during recovery sleep. Cortical …
and number of electroencephalogram (EEG) slow waves during recovery sleep. Cortical …
Sleep and circadian rhythms: do sleep centers talk back to the clock?
CS Colwell, S Michel - Nature neuroscience, 2003 - nature.com
A homeostatic control mechanism that monitors and reacts to the need for sleep has been
thought to function independently of the brain's circadian clock in previous studies. Now …
thought to function independently of the brain's circadian clock in previous studies. Now …