A Single Nucleotide Polymorphism in the 5′ Untranslated Region of the EGF Gene Is Associated with Occurrence and Malignant Progression of Gastric Cancer
Y Hamai, S Matsumura, K Matsusaki, Y Kitadai… - Pathobiology, 2005 - karger.com
Objective: Epidermal growth factor (EGF) has many biological functions and plays an
important role in the progression of various tumors including gastric cancer. An AG single …
important role in the progression of various tumors including gastric cancer. An AG single …
No Association Between EGF Gene Polymorphism and Gastric Cancer
Y Goto, T Ando, H Goto, N Hamajima - Cancer Epidemiology Biomarkers & …, 2005 - AACR
The etiology of gastric cancer is not well-understood. Epidermal growth factor (EGF)
transduces growth signals to mitogen-activated protein kinase via RAS and BRAF, and …
transduces growth signals to mitogen-activated protein kinase via RAS and BRAF, and …
Variant genotypes and haplotypes of the epidermal growth factor gene promoter are associated with a decreased risk of gastric cancer in a high‐risk Chinese …
G Jin, R Miao, Y Deng, Z Hu, Y Zhou, Y Tan… - Cancer …, 2007 - Wiley Online Library
Epidermal growth factor (EGF), a ligand of the EGF receptor, plays a critical role in the
development of gastric cancer. Genetic variants in its promoter region may influence …
development of gastric cancer. Genetic variants in its promoter region may influence …
Association between EGF promoter polymorphisms and cancer risk: a meta-analysis
W Xu, Y Li, X Wang, B Chen, S Liu, Y Wang, W Zhao… - Medical Oncology, 2010 - Springer
EGF promoter polymorphisms are observed to modulate EGF levels and thought to have
effect on susceptibility to various carcinomas but the results are inconsistent. In this meta …
effect on susceptibility to various carcinomas but the results are inconsistent. In this meta …
EGF+ 61A> G polymorphism and gastrointestinal cancer risk: a HuGE review and meta-analysis
Y Piao, Z Liu, Z Ding, L Xu, F Guo, Q Sun, X Xie - Gene, 2013 - Elsevier
Emerging evidences from preclinical and clinical studies have shown that epidermal growth
factor (EGF) has some effectiveness against endogenously arising carcinogenesis …
factor (EGF) has some effectiveness against endogenously arising carcinogenesis …
[HTML][HTML] Association between EGF+ 61A/G polymorphism and gastric cancer in Caucasians
AP Araújo, BM Costa, AL Pinto-Correia… - World journal of …, 2011 - ncbi.nlm.nih.gov
AIM: To investigate the association between epidermal growth factor (EGF)+ 61A/G
polymorphism and susceptibility to gastric cancer, through a cross-sectional study …
polymorphism and susceptibility to gastric cancer, through a cross-sectional study …
Amplification of epidermal growth factor receptor gene and its relationship to survival in human gastric cancer
Y Hirono, K Tsugawa, S Fushida, I Ninomiya… - Oncology, 1995 - karger.com
The correlation between the clinical features in 103 patients with primary gastric carcinoma
and amplification of epidermal growth factor receptor (EGFR) gene was analyzed …
and amplification of epidermal growth factor receptor (EGFR) gene was analyzed …
[HTML][HTML] Association among polymorphisms in EGFR gene exons, lifestyle and risk of gastric cancer with gender differences in Chinese Han subjects
J Zhang, Z Zhan, J Wu, C Zhang, Y Yang, S Tong… - PLoS …, 2013 - journals.plos.org
Background The epidermal growth factor receptor (EGFR) gene plays a key role in tumor
survival, invasion, angiogenesis, and metastatic spread. Recent studies showed that gastric …
survival, invasion, angiogenesis, and metastatic spread. Recent studies showed that gastric …
Epidermal growth factor (EGF) A61G polymorphism and EGF gene expression in normal colon tissue from patients with colorectal cancer
KLG Spindler, JN Nielsen, D Ornskov… - Acta …, 2007 - Taylor & Francis
Introduction. EGF/EGFR interactions are important mechanisms behind colorectal tumour
development and growth. Recently a single nucleotide polymorphism in the EGF gene has …
development and growth. Recently a single nucleotide polymorphism in the EGF gene has …
Association between epidermal growth factor polymorphism and esophageal squamous cell carcinoma susceptibility
L Cui, XM Pan, CF Ma, J Shang-Guan, HB Yu… - Digestive diseases and …, 2010 - Springer
Genetic factors are known to be important in the development of esophageal squamous cell
carcinoma (ESCC). Epidermal growth factor (EGF) can activate several signaling pathways …
carcinoma (ESCC). Epidermal growth factor (EGF) can activate several signaling pathways …
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