Nucleus accumbens acetylcholine and food intake: decreased muscarinic tone reduces feeding but not food-seeking

WE Pratt, K Blackstone - Behavioural brain research, 2009 - Elsevier
Separate groups of food-deprived rats were given 2h access to food after receiving bilateral
nucleus accumbens infusions of the muscarinic antagonist scopolamine methyl bromide (at …

Muscarinic receptor antagonism causes a functional alteration in nucleus accumbens μ-opiate-mediated feeding behavior

ML Perry, BA Baldo, ME Andrzejewski… - Behavioural brain …, 2009 - Elsevier
Intra-nucleus accumbens (Acb) infusion of cholinergic muscarinic antagonist, scopolamine
(10μg/0.5 μl), markedly reduced fat intake elicited by intra-Acb treatment of the μ-opioid …

Nucleus accumbens acetylcholine regulates appetitive learning and motivation for food via activation of muscarinic receptors.

WE Pratt, AE Kelley - Behavioral neuroscience, 2004 - psycnet.apa.org
These experiments tested whether nucleus accumbens muscarinic or nicotinic acetylcholine
receptor activation is required for rats to learn to lever press for sucrose. Muscarinic …

Increases in food intake or food-seeking behavior induced by GABAergic, opioid, or dopaminergic stimulation of the nucleus accumbens: is it hunger?

EC Hanlon, BA Baldo, K Sadeghian, AE Kelley - Psychopharmacology, 2004 - Springer
Rationale Previous work has shown that stimulation of GABAergic, opioid, or dopaminergic
systems within the nucleus accumbens modulates food intake and food-seeking behavior …

Muscarinic receptor antagonism of the nucleus accumbens core causes avoidance to flavor and spatial cues.

WE Pratt, RC Spencer, AE Kelley - Behavioral neuroscience, 2007 - psycnet.apa.org
Pharmacological blockade of muscarinic receptors in the nucleus accumbens reduces food
intake and instrumental behaviors that are reinforced by food delivery. Nucleus accumbens …

Muscarinic, but not nicotinic, acetylcholine receptor blockade in the ventral tegmental area attenuates cue-induced sucrose-seeking

NA Addy, EJ Nunes, RJ Wickham - Behavioural brain research, 2015 - Elsevier
The mesolimbic dopamine (DA) system is known to play a role in cue-mediated reward-
seeking for natural rewards and drugs of abuse. Specifically, cholinergic and glutamatergic …

Blockade of muscarinic acetylcholine receptors in the ventral tegmental area disrupts food-related learning in rats

R Sharf, R Ranaldi - Psychopharmacology, 2006 - Springer
Rationale Stimulation of ventral tegmental area (VTA) muscarinic acetylcholine receptors
(mAChRs) is implicated in feeding. Objective To investigate the effects of mAChR blockade …

Nucleus accumbens neurotransmission and effort-related choice behavior in food motivation: effects of drugs acting on dopamine, adenosine, and muscarinic …

EJ Nunes, PA Randall, S Podurgiel, M Correa… - Neuroscience & …, 2013 - Elsevier
Mesolimbic dopamine (DA) is a critical component of the brain circuitry regulating behavioral
activation and effort-related processes. Although nucleus accumbens (NAc) DA depletions …

GABA in the nucleus accumbens shell participates in the central regulation of feeding behavior

TR Stratford, AE Kelley - Journal of Neuroscience, 1997 - Soc Neuroscience
We have demonstrated previously that injections of 6, 7-dinitroquinoxaline-2, 3-dione into
the nucleus accumbens shell (AcbSh) elicits pronounced feeding in satiated rats. This …

Effects of feeding and drinking on acetylcholine release in the nucleus accumbens, striatum, and hippocampus of freely behaving rats

GP Mark, P Rada, E Pothos… - Journal of …, 1992 - Wiley Online Library
Extracellular levels of acetylcholine (ACh) were measured in the nucleus accumbens (NAC),
striatum (STR), and hippocampus (HIPP) using microdialysis in 30‐min intervals before …