Prior research has shown that glutamate and dopamine receptors in the nucleus accumbens
(NAcc) core are critical for the learning of an instrumental response for food reinforcement. It …

The aims of the present study were (1) to determine whether selective lesions of the
accumbens cholinergic interneurons impair feeding and body weight regulation, and (2) to …

MK-801, a noncompetitive N-methyl-d-aspartate (NMDA) receptor antagonist, enhances
gastric emptying while increasing food intake. Although our previously reported results …

Rationale: Endogenous opioids have been implicated in the hedonic evaluation of food and
palatability. Opioids may also be involved in alcohol intake, as there is a positive correlation …

Noradrenergic projections from the dorsomedial medulla reach the shell of the nucleus
accumbens (NAcc), a structure implicated in both reward and feeding behavior. Despite this …

The high attrition rates for dietary interventions aimed at promoting a healthier body mass
may be caused, at least in part, by constant exposure to environmental stimuli that are …

The present study tested whether presentation of a taste cue would support conditioned
suppression of dopamine in the nucleus accumbens (NAcc) following a single taste–drug …

Substantial evidence suggests that pharmacological manipulations of neural serotonin
pathways influence ingestive behaviors. Despite the known role of the nucleus accumbens …

Endogenous opioid peptides within the nucleus accumbens, a forebrain site critical for the
regulation of reward-related behavior, are believed to play an important role in the control of …

Binge eating, a central feature of multiple eating disorders, is characterized by excessive
consumption occurring during discrete, often brief, intervals. Highly palatable foods play an …