Feeding and systemic D-amphetamine increase extracellular acetylcholine in the medial thalamus: a possible reward enabling function

P Rada, L Hernandez, BG Hoebel - Neuroscience letters, 2007 - Elsevier
Acetylcholine neurons that project forward from the midbrain are known to enable
dopaminergic reward functions in the ventral tegmental area. The question is whether …

Opioid receptor antagonism in the nucleus accumbens fails to block the expression of sugar-conditioned flavor preferences in rats

SY Bernal, K Touzani, M Gerges, Y Abayev… - Pharmacology …, 2010 - Elsevier
In our prior studies, systemic administration of the opioid receptor antagonist naltrexone
(NTX) did not block flavor preference conditioning by the sweet taste or post-oral actions of …

CRF–CRF1 receptor system in the central and basolateral nuclei of the amygdala differentially mediates excessive eating of palatable food

A Iemolo, A Blasio, SA St Cyr, F Jiang… - …, 2013 - nature.com
Highly palatable foods and dieting are major contributing factors for the development of
compulsive eating in obesity and eating disorders. We previously demonstrated that …

Acetylcholine release in ventral tegmental area by hypothalamic self-stimulation, eating, and drinking

PV Rada, GP Mark, JJ Yeomans, BG Hoebel - … Biochemistry and Behavior, 2000 - Elsevier
Evidence is presented for an acetylcholine (ACh) input to the midbrain ventral tegmental
area (VTA) as part of a system for self-stimulation and ingestive behavior. Male rats were …

Nucleus accumbens dopamine and the regulation of effort in food-seeking behavior: implications for studies of natural motivation, psychiatry, and drug abuse

JD Salamone, M Correa, S Mingote… - Journal of Pharmacology …, 2003 - ASPET
For several decades, it has been suggested that dopamine (DA), especially in nucleus
accumbens, mediates the primary reinforcing characteristics of natural stimuli such as food …

A pharmacological analysis of the substrates underlying conditioned feeding induced by repeated opioid stimulation of the nucleus accumbens

AE Kelley, VP Bakshi, S Fleming… - …, 2000 - Elsevier
It has previously been demonstrated that stimulation of opiate receptors within the nucleus
accumbens results in marked hyperphagia, perhaps reflecting enhancement of taste …

Intra-accumbens injections of the adenosine A2A agonist CGS 21680 affect effort-related choice behavior in rats

L Font, S Mingote, AM Farrar, M Pereira, L Worden… - …, 2008 - Springer
Rationale Nucleus accumbens dopamine (DA) participates in the modulation of instrumental
behavior, including aspects of behavioral activation and effort-related choice behavior. Rats …

Food intake after diazepam, morphine or muscimol: microinjections in the nucleus accumbens shell

AHV Söderpalm, KC Berridge - Pharmacology Biochemistry and Behavior, 2000 - Elsevier
SÖDERPALM, AHV AND KC BERRIDGE. Food intake after diazepam, morphine, or
muscimol: Microinjections in the nucleus accumbens shell. PHARMACOL BIOCHEM BEHAV …

CB1 receptors modulate the intake of a sweetened-fat diet in response to mu-opioid receptor stimulation of the nucleus accumbens

MJ Skelly, EG Guy, AC Howlett, WE Pratt - Pharmacology Biochemistry and …, 2010 - Elsevier
Previous research has demonstrated that concurrent systemic administration of CB1
cannabinoid and mu-opioid receptor agonists increases feeding in rats. However, the …

Daily bingeing on sugar repeatedly releases dopamine in the accumbens shell

P Rada, NM Avena, BG Hoebel - Neuroscience, 2005 - Elsevier
Most drugs of abuse increase dopamine (DA) in the nucleus accumbens (NAc), and do so
every time as a pharmacological response. Palatable food also releases accumbens-shell …