Traumatic brain injury (TBI) is a serious global health problem, many individuals live with TBI-
related neurological dysfunction. A lack of biomarkers of TBI has impeded medication …

Annually, more than a million persons experience traumatic brain injury (TBI) in the US and
a substantial proportion of this population develop debilitating neurological disorders, such …

Cerebral inflammatory responses may initiate secondary cascades following traumatic brain
injury (TBI). Changes in the expression of both cytokines and chemokines may activate …

Background Traumatic brain injury (TBI) with its associated morbidity is a major area of
unmet medical need that lacks effective therapies. TBI initiates a neuroinflammatory cascade …

Cerebral gene expressions change in response to traumatic brain injury (TBI), and future
trauma treatment may improve with increased knowledge about these regulations. We …

Abstract Operation Brain Trauma Therapy (OBTT) is a multicenter pre-clinical drug
screening consortium testing promising therapies for traumatic brain injury (TBI) in three well …

There are no existing treatments for the long-term degenerative effects of traumatic brain
injury (TBI). This is due, in part, to our limited understanding of chronic TBI and uncertainty …

Background Traumatic brain injury (TBI) evokes a systemic immune response including
leukocyte migration into the brain and release of pro-inflammatory cytokines; however, the …

Cytokine mediated inflammation likely plays an important role in secondary pathology after
traumatic brain injury (TBI). The aim of this study was to elucidate secondary cytokine …

Traumatic brain injury (TBI) affects millions of people worldwide every year. The primary
impact initiates the secretion of pro-and anti-inflammatory factors, subsequent recruitment of …