Autophagy is an evolutionarily conserved cellular process in which macromolecules
undergo lysosomal degradation. It fulfills essential roles in quality controlling cellular …

Autophagy, one of two major intracellular degradation pathways, plays a critical role in
energy homeostasis and the quality control of macromolecules and intracellular organelles …

Autophagy not only constitutes a robust barrier against malignant transformation at the cell-
intrinsic level, but also contributes to the organismal control of potentially oncogenic cells …

Autophagy is an important cellular degradation pathway with a central role in metabolism as
well as basic quality control, two processes inextricably linked to ageing. A decrease in …

Macroautophagy (referred to here as autophagy) is induced by starvation to capture and
degrade intracellular proteins and organelles in lysosomes, which recycles intracellular …

Macroautophagy (autophagy) is a conserved lysosomal degradation process essential for
cellular homeostasis and adaption to stress. Accumulating evidence indicates that …

Autophagy is a cellular degradation pathway for the clearance of damaged or superfluous
proteins and organelles. The recycling of these intracellular constituents also serves as an …

When mammalian cells and animals face a variety of internal or external stresses, they need
to make homeostatic changes so as to cope with various stresses. To this end, mammalian …

Autophagy is a self-degradation pathway, in which cytoplasmic material is sequestered in
double-membrane vesicles and delivered to the lysosome for degradation. Under basal …

Autophagy is a lysosomal degradation process crucial for adaptation to stress and cellular
homeostasis. In cancer, autophagy has been demonstrated to serve multifaceted roles in …