Ursodeoxycholic acid inhibits inflammatory responses and promotes functional recovery after spinal cord injury in rats
The aim of this study was to investigate the anti-inflammatory effects by ursodeoxycholic acid
(UDCA) in rats with a spinal cord injury (SCI). A moderate mechanical compression injury …
(UDCA) in rats with a spinal cord injury (SCI). A moderate mechanical compression injury …
[HTML][HTML] Anti-inflammatory effect of Tauroursodeoxycholic acid in RAW 264.7 macrophages, Bone marrow-derived macrophages, BV2 microglial cells, and spinal cord …
This study aimed to investigate the anti-inflammatory effects of tauroursodeoxycholic acid
(TUDCA) after spinal cord injury (SCI) in rats. We induced an inflammatory process in RAW …
(TUDCA) after spinal cord injury (SCI) in rats. We induced an inflammatory process in RAW …
[HTML][HTML] Neuroprotective effects and impact on caspase-12 expression of tauroursodeoxycholic acid after acute spinal cord injury in rats
Y Dong, L Miao, L Hei, L Lin, H Ding - International journal of …, 2015 - ncbi.nlm.nih.gov
Objective: To observe the effects of tauroursodeoxycholic acid (TUDCA) on nerve function
after acute spinal cord injury (SCI) in rats, observe its effect on neuronal apoptosis and …
after acute spinal cord injury (SCI) in rats, observe its effect on neuronal apoptosis and …
[HTML][HTML] Tauroursodeoxycholic acid alleviates secondary injury in spinal cord injury mice by reducing oxidative stress, apoptosis, and inflammatory response
Y Hou, J Luan, T Huang, T Deng, X Li, Z Xiao… - Journal of …, 2021 - Springer
Background Tauroursodeoxycholic acid (TUDCA) is a hydrophilic bile acid derivative, which
has been demonstrated to have neuroprotective effects in different neurological disease …
has been demonstrated to have neuroprotective effects in different neurological disease …
Injectable hydrogel containing tauroursodeoxycholic acid for anti-neuroinflammatory therapy after spinal cord injury in rats
We investigate the anti-inflammatory effects of injectable hydrogel containing
tauroursodeoxycholic acid (TUDCA) in a spinal cord injury (SCI) model. To this end, TUDCA …
tauroursodeoxycholic acid (TUDCA) in a spinal cord injury (SCI) model. To this end, TUDCA …
Tauroursodeoxycholic acid alleviates secondary injury in the spinal cord via up-regulation of CIBZ gene
Z Zhang, J Chen, F Chen, D Yu, R Li, C Lv… - Cell Stress and …, 2018 - Springer
Spinal cord injury (SCI) is generally divided into primary and secondary injuries, and
apoptosis is an important event of the secondary injury. As an endogenous bile acid and …
apoptosis is an important event of the secondary injury. As an endogenous bile acid and …
[HTML][HTML] Tauroursodeoxycholic acid reduces neuroinflammation but does not support long term functional recovery of rats with spinal cord injury
S Wu, C García-Rama, L Romero-Ramírez… - Biomedicines, 2022 - mdpi.com
The bile acid tauroursodeoxycholic acid (TUDCA) reduces cell death under oxidative stress
and inflammation. Implants of bone marrow-derived stromal cells (bmSC) are currently …
and inflammation. Implants of bone marrow-derived stromal cells (bmSC) are currently …
Tauroursodeoxycholic acid and secondary damage after spinal cord injury in rats
A Çolak, B Kelten, A Sağmanligil, O Akdemir… - Journal of Clinical …, 2008 - Elsevier
Greater clinical understanding of the pivotal role of apoptosis in spinal cord injury (SCI) has
led to new and innovative apoptosis-based therapies for patients with an SCI …
led to new and innovative apoptosis-based therapies for patients with an SCI …
[HTML][HTML] Ursodeoxycholic acid as a potential alternative therapeutic approach for neurodegenerative disorders: effects on cell apoptosis, oxidative stress and …
F Huang - Brain, behavior, & immunity-health, 2021 - Elsevier
Ursodeoxycholic acid (UDCA) is a bile acid component with anti-apoptotic, anti-oxidant and
anti-inflammatory properties. It has been used in clinical medicine for liver diseases for …
anti-inflammatory properties. It has been used in clinical medicine for liver diseases for …
[HTML][HTML] Tauroursodeoxycholic Acid Inhibited Apoptosis and Oxidative Stress in H2O2-Induced BMSC Death via Modulating the Nrf-2 Signaling Pathway: the …
J Weng, L Wang, K Wang, H Su, D Luo, H Yang… - Molecular …, 2023 - Springer
Spinal cord injury (SCI) is a prevalent and significant injury to the central nervous system,
resulting in severe consequences. This injury is characterized by motor, sensory, and …
resulting in severe consequences. This injury is characterized by motor, sensory, and …
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