The interplay of phenotype and genotype in Cryptococcus neoformans disease
S Altamirano, KM Jackson, K Nielsen - Bioscience Reports, 2020 - portlandpress.com
Cryptococcus neoformans is an opportunistic fungal pathogen that causes life-threatening
meningitis primarily in immunocompromised individuals. In order to survive and proliferate …
meningitis primarily in immunocompromised individuals. In order to survive and proliferate …
Convergent microevolution of Cryptococcus neoformans hypervirulence in the laboratory and the clinic
Reference strains are a key component of laboratory research, providing a common
background allowing for comparisons across a community of researchers. However …
background allowing for comparisons across a community of researchers. However …
Lineages derived from Cryptococcus neoformans type strain H99 support a link between the capacity to be pleomorphic and virulence
The pathogenic yeast Cryptococcus neoformans causes nearly 200,000 deaths annually in
immunocompromised individuals. Cryptococcus cells can undergo substantial …
immunocompromised individuals. Cryptococcus cells can undergo substantial …
Cryptococcus neoformans: morphogenesis, infection, and evolution
X Lin - Infection, Genetics and Evolution, 2009 - Elsevier
Cryptococcus neoformans is the major causative agent of fungal meningoencephalitis in
both immunocompromised and immunocompetent individuals. During infection, this fungus …
both immunocompromised and immunocompetent individuals. During infection, this fungus …
Importance of Clinical Isolates in Cryptococcus neoformans Research
KM Jackson, M Ding, K Nielsen - Journal of Fungi, 2023 - mdpi.com
The human pathogenic fungus Cryptococcus neoformans is a global health concern.
Previous research in the field has focused on studies using reference strains to identify …
Previous research in the field has focused on studies using reference strains to identify …
Comparative Genomics of Serial Isolates of Cryptococcus neoformans Reveals Gene Associated With Carbon Utilization and Virulence
KL Ormerod, CA Morrow, EWL Chow… - G3: Genes …, 2013 - academic.oup.com
The opportunistic fungal pathogen Cryptococcus neoformans is a leading cause of mortality
among the human immunodeficiency virus/acquired immunodeficiency syndrome …
among the human immunodeficiency virus/acquired immunodeficiency syndrome …
Microevolution of Serial Clinical Isolates of Cryptococcus neoformans var. grubii and C. gattii
The pathogenic species of Cryptococcus are a major cause of mortality owing to severe
infections in immunocompromised as well as immunocompetent individuals. Although …
infections in immunocompromised as well as immunocompetent individuals. Although …
Associations between Cryptococcus Genotypes, Phenotypes, and Clinical Parameters of Human Disease: A Review
MC Montoya, PM Magwene, JR Perfect - Journal of Fungi, 2021 - mdpi.com
The genus Cryptococcus contains two primary species complexes that are significant
opportunistic human fungal pathogens: C. neoformans and C. gattii. In humans …
opportunistic human fungal pathogens: C. neoformans and C. gattii. In humans …
Identification of pathogen genomic differences that impact human immune response and disease during Cryptococcus neoformans infection
AC Gerstein, KM Jackson, TR McDonald, Y Wang… - MBio, 2019 - Am Soc Microbiol
Patient outcomes during infection are due to a complex interplay between the quality of
medical care, host immunity factors, and the infecting pathogen's characteristics. To probe …
medical care, host immunity factors, and the infecting pathogen's characteristics. To probe …
Microevolution of a Standard Strain ofCryptococcus neoformans Resulting in Differences in Virulence and Other Phenotypes
SP Franzot, J Mukherjee, R Cherniak… - Infection and …, 1998 - Am Soc Microbiol
Cryptococcus neoformans is a major fungal pathogen for patients with debilitated immune
systems. However, no information is available on the stability of virulence or of phenotypes …
systems. However, no information is available on the stability of virulence or of phenotypes …