Highlights•Bioactivity-based discovery has yielded an array of new antibacterial compounds
and targets.•Exploiting phenotypic determinants and intraspecies and interspecies …

In the relentless pursuit of innovative therapeutic agents, natural products have emerged as
a transformative avenue in the battle against infectious diseases. This Special Issue, entitled …

Natural products have been a rich source of antibacterial drugs for many decades, but
investments in this area have declined over the past two decades. The purpose of this …

Phytochemicals are secondary metabolites mostly produced by higher plants to enable them
to survive under various biotic and abiotic stresses. Scientific reports exhibited that these …

Natural extracts have been and continue to be used to treat a wide range of medical
conditions, from infectious diseases to cancer, based on their convenience and therapeutic …

Natural products have been regarded as important sources that could produce potential
chemotherapeutic agents. In the search for new bioactive entities, investigations were …

The spread of resistant organisms is producing a human health crisis, as we are witnessing
the emergence of pathogens resistant to all available antibiotics. An increase in chronic …

Plants being capable of synthesizing a vast array of secondary metabolites with
antimicrobial potential are a prospective source of new therapeutic agents. Methods for …

Infectious diseases, in particular bacterial infections, are the leading cause of morbidity and
mortality posing a global threat to human health. The emergence of antibiotic resistance has …

Pasteur and Joubert, in 1877, were among the first to recognize the potential of microbial
products as therapeutic agents and demonstrated that common microorganisms could …