Although new antibiofilm agents have been developed to prevent and eliminate pathogenic
biofilms, their widespread clinical use is hindered by poor biocompatibility and …

Importance of the field: Current antibiotics have classically been developed to treat
infections involving planktonic bacterial populations in acute infection settings and are …

Biofilms have attracted increasing attention in recent years. Many bacterial infections are
associated with biofilm formation. A bacterial biofilm is an aggregated membrane-like …

This commentary highlights several avenues currently being pursued in research labs to the
development of new anti-biofilm pharmaceuticals. There is a real need for alternative …

Biofilms are aggregate of microorganisms in which cells are frequently embedded within a
self-produced matrix of extracellular polymeric substance (EPS) and adhere to each other …

Highlights•Currently used antibiotics were developed to target planktonic bacteria.•Recent
discoveries on biofilm properties led to promising anti-biofilm strategies.•Biofilm inhibition …

Biofilms are intricate multicellular structures created by microorganisms on living (biotic) or
nonliving (abiotic) surfaces. Medically, biofilms often lead to persistent infections, increased …

Biofilms are formed by the attachment of single or mixed microbial communities to a variety
of biological and/or synthetic surfaces. Biofilm micro-organisms benefit from many …

Medical device related infections are a significant and growing source of morbidity and
mortality. Biofilm formation is a common feature of medical device infections that is not …

In the biofilm form, bacteria are more resistant to various antimicrobial treatments. Bacteria in
a biofilm can also survive harsh conditions and withstand the host's immune system …