Granulocyte and monocyte adsorptive apheresis in the treatment of active distal ulcerative colitis: a prospective, pilot study

T Yamamoto, S Umegae, T Kitagawa… - Alimentary …, 2004 - Wiley Online Library
Aim: To assess safety and clinical efficacy of granulocyte and monocyte adsorptive
apheresis for distal ulcerative colitis. Methods: Granulocyte and monocyte adsorptive …

Factors associated with the outcomes in ulcerative colitis patients undergoing granulocyte and monocyte adsorptive apheresis as remission induction therapy: A …

Y Ishiguro, T Ohmori, K Umemura… - … Apheresis and Dialysis, 2021 - Wiley Online Library
Ulcerative colitis (UC) patients harbor activated myeloid leukocytes, which exacerbate and
perpetuate UC by releasing inflammatory cytokines. Granulocyte and monocyte adsorptive …

Granulocyte and monocyte apheresis as an adjunctive therapy to induce and maintain clinical remission in ulcerative colitis: a systematic review and meta-analysis

S Kiss, D Németh, P Hegyi, M Földi, Z Szakács… - BMJ open, 2021 - bmjopen.bmj.com
Objective The goal of treatment in ulcerative colitis (UC) is to induce and maintain remission.
The addition of granulocyte and monocyte apheresis (GMA) to conventional therapy may be …

Long-term clinical impact of early introduction of granulocyte and monocyte adsorptive apheresis in new onset, moderately active, extensive ulcerative colitis

T Yamamoto, S Umegae… - Journal of Crohn's and …, 2012 - academic.oup.com
Background and aims: The efficacy of granulocyte and monocyte adsorptive apheresis
(GMA) for patients with a first episode of ulcerative colitis (UC) has been scarcely reported …

[HTML][HTML] Selective granulocyte and monocyte apheresis in inflammatory bowel disease: Its past, present and future

XL Chen, JW Mao, YD Wang - World Journal of Gastrointestinal …, 2020 - ncbi.nlm.nih.gov
The etiology and pathogenesis of inflammatory bowel disease (IBD), including ulcerative
colitis and Crohn's disease, are not fully understood so far. Therefore, IBD still remains …

Adacolumn selective leukocyte adsorption apheresis in patients with active ulcerative colitis: clinical efficacy, effects on plasma IL-8, and expression of Toll-like …

H Aoki, K Nakamura, Y Yoshimatsu, Y Tsuda… - Digestive diseases and …, 2007 - Springer
Adacolumn selective granulocyte and monocyte apheresis (GMA) depletes activated
leukocytes in patients with ulcerative colitis (UC). However, this per se cannot fully explain …

[HTML][HTML] Treating inflammatory bowel disease by adsorptive leucocytapheresis: a desire to treat without drugs

AR Saniabadi, T Tanaka, T Ohmori… - World Journal of …, 2014 - ncbi.nlm.nih.gov
Ulcerative colitis and Crohn's disease are the major phenotypes of the idiopathic
inflammatory bowel disease (IBD), which afflicts millions of individuals throughout the world …

Clinical and endoscopic features of responders and non-responders to adsorptive leucocytapheresis: a report based on 120 patients with active ulcerative colitis

T Tanaka, H Okanobu, Y Kuga, Y Yoshifuku… - … clinique et biologique, 2010 - Elsevier
BACKGROUND AND OBJECTIVE: Elevated/activated myeloid leucocytes, like the CD14 (+)
CD16 (+) monocytes are sources of TNF-α, and therefore, selective depletion of these cells …

Efficacy and endoscopic prediction of cytapheresis therapy in patients with refractory and steroid‐dependent ulcerative colitis

K Watanabe, N Oshitani, N Kamata… - Alimentary …, 2006 - Wiley Online Library
Background Recently, it has been proved in Japan that granulocyte and monocyte
adsorption apheresis (GCAP) and leukocytapheresis (LCAP) are effective and safe for …

[HTML][HTML] Induction of mucosal healing by intensive granulocyte/monocyte adsorptive apheresis (GMA) without use of corticosteroids in patients with ulcerative colitis …

T Fukuchi, K Kawashima, H Koga… - Journal of Clinical …, 2022 - ncbi.nlm.nih.gov
This study examined the long-term maintenance rate after inducing remission by intensive
granulocyte/monocyte adsorptive apheresis (GMA) without use of corticosteroids (CS) and …