The protein C pathway plays a critical role in the negative regulation of the blood clotting
process. We recently identified an endothelial cell receptor for protein C/activated protein C …

Plasma protein C functions as an anticoagulant when it is converted to the active form of
serine protease. Protein C activation has been found to be mediated by the endothelial cell …

The endothelial cell protein C receptor (EPCR) functions as an important regulator of the
protein C anticoagulant pathway by binding protein C and enhancing activation by the …

Protein C is an important regulatory mechanism of blood coagulation. Protein C functions as
an anticoagulant when converted to the active serine protease form on the endothelial cell …

Background The protein C anticoagulant pathway is critical to the control of hemostasis.
Thrombomodulin and a newly identified receptor for protein C/activated protein C, EPCR …

A soluble form of the endothelial cell protein C receptor (EPCR) was analyzed for the ability
to modulate the functional properties of protein C and activated protein C (APC). In a plasma …

The molecular links between inflammation and coagulation are unquestioned. Inflammation
promotes coagulation by leading to intravascular tissue factor expression, eliciting the …

The endothelial protein C receptor (EPCR) plays an anticoagulant role by improving protein
C activation. Although low levels of activated protein C (APC) constitute a thrombosis risk …

The endothelial cell protein C receptor@ PCR) is the most recently identified member O {,
the protein C anticoagulant pathway. Protein C and activaibd protein C (APC) bind to EPCR …

Endothelial cell protein C receptor (EPCR) augments protein C activation by the thrombin-
thrombomodulin complex about 5-fold in vitro. Augmentation is EPCR concentration …