Cellular uptake and fate of PEGylated gold nanoparticles is dependent on both cell-penetration peptides and particle size
E Oh, JB Delehanty, KE Sapsford, K Susumu… - ACS …, 2011 - ACS Publications
Numerous studies have examined how the cellular delivery of gold nanoparticles (AuNPs) is
influenced by different physical and chemical characteristics; however, the complex …
influenced by different physical and chemical characteristics; however, the complex …
Peptide modified gold nanoparticles for improved cellular uptake, nuclear transport, and intracellular retention
Gold nanoparticles (GNPs) are being extensively used in cancer therapeutic applications
due to their ability to act both as an anticancer drug carrier in chemotherapy and as a dose …
due to their ability to act both as an anticancer drug carrier in chemotherapy and as a dose …
A reexamination of active and passive tumor targeting by using rod-shaped gold nanocrystals and covalently conjugated peptide ligands
The targeted delivery of nanoparticles to solid tumors is one of the most important and
challenging problems in cancer nanomedicine, but the detailed delivery mechanisms and …
challenging problems in cancer nanomedicine, but the detailed delivery mechanisms and …
Cellular trajectories of peptide-modified gold particle complexes: comparison of nuclear localization signals and peptide transduction domains
Gold nanoparticles modified with nuclear localization peptides were synthesized and
evaluated for their subcellular distribution in HeLa human cervical epithelium cells, 3T3/NIH …
evaluated for their subcellular distribution in HeLa human cervical epithelium cells, 3T3/NIH …
Cellular uptake of gold nanoparticles triggered by host–guest interactions
J Mosquera, M Henriksen-Lacey, I García… - Journal of the …, 2018 - ACS Publications
We describe an approach to regulate the cellular uptake of small gold nanoparticles using
supramolecular chemistry. The strategy relies on the functionalization of AuNPs with …
supramolecular chemistry. The strategy relies on the functionalization of AuNPs with …
Biologically inspired stealth peptide-capped gold nanoparticles
Introduction into the human body makes most nanoparticle systems susceptible to
aggregation via nonspecific protein binding. Here, we developed a peptide-capped gold …
aggregation via nonspecific protein binding. Here, we developed a peptide-capped gold …
Mammalian Cells Exocytose Alkylated Gold Nanoparticles via Extracellular Vesicles
Understanding the exocytosis of nanoparticles (NPs) from cells is valuable because it
informs design rules of NPs that support desirable cellular retention for nanomedicine …
informs design rules of NPs that support desirable cellular retention for nanomedicine …
Synthesis, stability, and cellular internalization of gold nanoparticles containing mixed peptide− poly (ethylene glycol) monolayers
Y Liu, MK Shipton, J Ryan, ED Kaufman… - Analytical …, 2007 - ACS Publications
Gold nanoparticles have shown great promise as therapeutics, therapeutic delivery vectors,
and intracellular imaging agents. For many biomedical applications, selective cell and …
and intracellular imaging agents. For many biomedical applications, selective cell and …
Effect of alkylation on the cellular uptake of polyethylene glycol-coated gold nanoparticles
Alkyl groups (C n H2 n+ 1) are prevalent in engineered bionanomaterials used for many
intracellular applications, yet how alkyl groups dictate the interactions between …
intracellular applications, yet how alkyl groups dictate the interactions between …
Multiplexed screening of cellular uptake of gold nanoparticles using laser desorption/ionization mass spectrometry
Gold nanoparticles (AuNPs) are highly promising candidates as drug delivery agents into
cells of interest. We describe for the first time the multiplexed analysis of nanoparticle uptake …
cells of interest. We describe for the first time the multiplexed analysis of nanoparticle uptake …
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