Updates and advances in multiple sclerosis neurotherapeutics
The multiple sclerosis (MS) neurotherapeutic landscape is rapidly evolving. New disease-
modifying therapies (DMTs) with improved efficacy and safety, in addition to an expanding …
modifying therapies (DMTs) with improved efficacy and safety, in addition to an expanding …
Updates on efficacy and safety outcomes of new and emerging disease modifying therapies and stem cell therapy for Multiple Sclerosis: A review
S Peterson, A Jalil, K Beard, M Kakara… - Multiple Sclerosis and …, 2022 - Elsevier
Multiple Sclerosis (MS) is a chronic neurodegenerative autoimmune disorder of the central
nervous system (CNS) and the most common cause of serious physical disability in working …
nervous system (CNS) and the most common cause of serious physical disability in working …
Failed, interrupted, or inconclusive trials on neuroprotective and neuroregenerative treatment strategies in multiple sclerosis: update 2015–2020
N Huntemann, L Rolfes, M Pawlitzki, T Ruck, S Pfeuffer… - Drugs, 2021 - Springer
In the recent past, a plethora of drugs have been approved for the treatment of multiple
sclerosis (MS). These therapeutics are mainly confined to immunomodulatory or …
sclerosis (MS). These therapeutics are mainly confined to immunomodulatory or …
Therapies for multiple sclerosis: translational achievements and outstanding needs
A Haghikia, R Hohlfeld, R Gold, L Fugger - Trends in Molecular Medicine, 2013 - cell.com
In recent years, multiple sclerosis (MS) research has progressed on several fronts,
prompting numerous clinical trials, primarily for immunotherapeutics. Although several new …
prompting numerous clinical trials, primarily for immunotherapeutics. Although several new …
Achievements and obstacles of remyelinating therapies in multiple sclerosis
M Stangel, T Kuhlmann, PM Matthews… - Nature Reviews …, 2017 - nature.com
Remyelination in the CNS is the natural process of damage repair in demyelinating
diseases such as multiple sclerosis (MS). However, remyelination becomes inadequate in …
diseases such as multiple sclerosis (MS). However, remyelination becomes inadequate in …
Stem cell therapies for progressive multiple sclerosis
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
characterized by demyelination and axonal degeneration. MS patients typically present with …
characterized by demyelination and axonal degeneration. MS patients typically present with …
Stem cell-based therapies for multiple sclerosis: current perspectives
FX Cuascut, GJ Hutton - Biomedicines, 2019 - mdpi.com
Multiple sclerosis (MS) is an inflammatory and neurodegenerative autoimmune disease of
the central nervous system (CNS). Disease-modifying therapies (DMT) targeting …
the central nervous system (CNS). Disease-modifying therapies (DMT) targeting …
New and emerging disease modifying therapies for multiple sclerosis
S Saidha, C Eckstein… - Annals of the New York …, 2012 - Wiley Online Library
Several disease‐modifying drugs (DMDs) are currently approved for the treatment of
multiple sclerosis (MS). Recently, there has been increased identification and development …
multiple sclerosis (MS). Recently, there has been increased identification and development …
Neuroprotection, regeneration and immunomodulation: broadening the therapeutic repertoire in multiple sclerosis
O Aktas, B Kieseier, HP Hartung - Trends in neurosciences, 2010 - cell.com
Multiple sclerosis (MS), an incurable but manageable disorder, is characterized by chronic
inflammatory demyelination and neurodegeneration in the central nervous system. Although …
inflammatory demyelination and neurodegeneration in the central nervous system. Although …
Toward the development of rational therapies in multiple sclerosis: what is on the horizon?
B Hemmer, HP Hartung - Annals of neurology, 2007 - Wiley Online Library
Although the cause of multiple sclerosis (MS) has remained obscure, many findings support
an autoimmune pathogenesis on the background of a complex interaction between multiple …
an autoimmune pathogenesis on the background of a complex interaction between multiple …