Amoeba predation of Cryptococcus neoformans results in pleiotropic changes to traits associated with virulence
MS Fu, LC Liporagi-Lopes, SR dos Santos, JL Tenor… - MBio, 2021 - Am Soc Microbiol
Amoeboid predators, such as amoebae, are proposed to select for survival traits in soil
microbes such as Cryptococcus neoformans; these traits can also function in animal …
microbes such as Cryptococcus neoformans; these traits can also function in animal …
[HTML][HTML] Dangerous Liaisons: Interactions of Cryptococcus neoformans with Host Phagocytes
EA Gaylord, HL Choy, TL Doering - Pathogens, 2020 - mdpi.com
Cryptococcus neoformans is an opportunistic fungal pathogen and a leading cause of death
in immunocompromised individuals. The interactions of this yeast with host phagocytes are …
in immunocompromised individuals. The interactions of this yeast with host phagocytes are …
The Intracellular Life of Cryptococcus neoformans
Cryptococcus neoformans is a fungal pathogen with worldwide distribution. Serological
studies of human populations show a high prevalence of human infection, which rarely …
studies of human populations show a high prevalence of human infection, which rarely …
Genetic analysis of Hsp90 function in Cryptococcus neoformans highlights key roles in stress tolerance and virulence
The opportunistic human fungal pathogen Cryptococcus neoformans has tremendous
impact on global health, causing 181,000 deaths annually. Current treatment options are …
impact on global health, causing 181,000 deaths annually. Current treatment options are …
[HTML][HTML] 'Division of labour' in response to host oxidative burst drives a fatal Cryptococcus gattii outbreak
Cryptococcus gattii is an emerging intracellular pathogen and the cause of the largest
primary outbreak of a life-threatening fungal disease in a healthy population. Outbreak …
primary outbreak of a life-threatening fungal disease in a healthy population. Outbreak …
The tools for virulence of Cryptococcus neoformans
Cryptococcus neoformans is a fungal pathogen that causes almost half a million deaths
each year. It is believed that most humans are infected with C. neoformans, possibly in a …
each year. It is believed that most humans are infected with C. neoformans, possibly in a …
[HTML][HTML] Modulation of Replicative Lifespan in Cryptococcus neoformans: Implications for Virulence
T Bouklas, N Jain, BC Fries - Frontiers in microbiology, 2017 - frontiersin.org
The fungal pathogen, Cryptococcus neoformans, has been shown to undergo replicative
aging. Old cells are characterized by advanced generational age and phenotypic changes …
aging. Old cells are characterized by advanced generational age and phenotypic changes …
Macrophage mitochondrial and stress response to ingestion of Cryptococcus neoformans
Human infection with Cryptococcus neoformans, a common fungal pathogen, follows
deposition of yeast spores in the lung alveoli. The subsequent host–pathogen interaction …
deposition of yeast spores in the lung alveoli. The subsequent host–pathogen interaction …
Expanding fungal pathogenesis: Cryptococcus breaks out of the opportunistic box
JW Kronstad, R Attarian, B Cadieux, J Choi… - Nature reviews …, 2011 - nature.com
Cryptococcus neoformans is generally considered to be an opportunistic fungal pathogen
because of its tendency to infect immunocompromised individuals, particularly those …
because of its tendency to infect immunocompromised individuals, particularly those …
The Cyclin Cln1 Controls Polyploid Titan Cell Formation following a Stress-Induced G2 Arrest in Cryptococcus
S Altamirano, Z Li, MS Fu, M Ding, SR Fulton, JM Yoder… - Mbio, 2021 - Am Soc Microbiol
The pathogenic yeast Cryptococcus neoformans produces polyploid titan cells in response
to the host lung environment that are critical for host adaptation and subsequent disease …
to the host lung environment that are critical for host adaptation and subsequent disease …