Carbapenemases are β-lactamases belonging to different Ambler classes (A, B, D) and can
be encoded by both chromosomal and plasmid-mediated genes. These enzymes represent …

The dramatic increase in the prevalence and clinical impact of infections caused by bacteria
producing carbapenemases is a global health concern. Carbapenemase production is …

Carbapenemases are β-lactamases that hydrolyze most β-lactams including carbapenems.
Carbapenemases are classified in four molecular classes; those belonging to class A are …

Carbapenemases are β-lactamases with versatile hydrolytic capacities. They have the ability
to hydrolyze penicillins, cephalosporins, monobactams, and carbapenems. Bacteria …

Introduction Carbapenemases are β-lactamases able to hydrolyze a wide range of β-lactam
antibiotics, including carbapenems. Carbapenemase production in Enterobacterales …

The emergence and rapid spread of carbapenemases in Enterobacteriaceae,
Pseudomonas and Acinetobacter (EPA) species is becoming a major public health crisis …

Carbapenemases, with versatile hydrolytic capacity against β-lactams, are now an important
cause of resistance of Gram-negative bacteria. The genes encoding for the acquired …

Acquired carbapenemases are emerging resistance determinants in Gram-negative
pathogens, including Enterobacteriaceae, Pseudomonas aeruginosa and other Gram …

Carbapenemases are β-lactamases that confer resistance to the carbapenems (eg,
imipenem, meropenem, ertapenem, and doripenem). Most often these enzymes confer …

Acquired carbapenemases pose one of the most pressing public health threats relating to
antibiotic resistance. In most countries, the number of carbapenemase-producing bacteria …