Moderate–severe traumatic brain injury causes delayed loss of white matter integrity: Evidence of fornix deterioration in the chronic stage of injury

A Adnan, A Crawley, D Mikulis, M Moscovitch… - Brain Injury, 2013 - Taylor & Francis
Objectives: To examine structural integrity loss in the fornix from 5–30 months after moderate
and severe traumatic brain injury (TBI) using diffusion tensor imaging. Methods: MRIs were …

A prospective diffusion tensor imaging study in mild traumatic brain injury

AR Mayer, J Ling, MV Mannell, C Gasparovic… - Neurology, 2010 - AAN Enterprises
Objectives: Only a handful of studies have investigated the nature, functional significance,
and course of white matter abnormalities associated with mild traumatic brain injury (mTBI) …

Chronic white matter changes detected using diffusion tensor imaging following adult traumatic brain injury and their relationship to cognition.

EJ Wallace, JL Mathias, L Ward, K Pannek… - …, 2020 - psycnet.apa.org
Objective: White matter (WM) changes detected using diffusion tensor imaging (DTI) are
reportedly related to cognitive outcomes following traumatic brain injury (TBI), but much …

Diffusion tensor imaging reveals elevated diffusivity of white matter microstructure that is independently associated with long-term outcome after mild traumatic brain …

EM Palacios, EL Yuh, CL Mac Donald… - Journal of …, 2022 - liebertpub.com
Diffusion tensor imaging (DTI) literature on single-center studies contains conflicting results
regarding acute effects of mild traumatic brain injury (mTBI) on white matter (WM) …

Use of diffusion tensor imaging to examine subacute white matter injury progression in moderate to severe traumatic brain injury

G Greenberg, DJ Mikulis, K Ng, D DeSouza… - Archives of physical …, 2008 - Elsevier
Greenberg G, Mikulis DJ, Ng K, DeSouza D, Green RE. Use of diffusion tensor imaging to
examine subacute white matter injury progression in moderate to severe traumatic brain …

Acute mild traumatic brain injury is not associated with white matter change on diffusion tensor imaging

T Ilvesmäki, TM Luoto, U Hakulinen, A Brander… - Brain, 2014 - academic.oup.com
This study was designed to (i) evaluate the influence of age on diffusion tensor imaging
measures of white matter assessed using tract-based spatial statistics;(ii) determine if mild …

Global white matter analysis of diffusion tensor images is predictive of injury severity in traumatic brain injury

RR Benson, SA Meda, S Vasudevan, Z Kou… - Journal of …, 2007 - liebertpub.com
Conventional clinical neuroimaging is insensitive to axonal injury in traumatic brain injury
(TBI). Immunocytochemical staining reveals changes to axonal morphology within hours …

Longitudinal examination of the relationship between changes in white matter organization and cognitive outcome in chronic TBI

KS Chiou, T Jiang, N Chiaravalloti, MJ Hoptman… - Brain injury, 2019 - Taylor & Francis
ABSTRACT Background and Objective: Changes in cerebral white matter organization have
been documented in acute phases of recovery from traumatic brain injury (TBI). However …

Spatiotemporal changes in diffusion, T2 and susceptibility of white matter following mild traumatic brain injury

W Li, JA Long, L Watts, Q Shen, Y Liu… - NMR in …, 2016 - Wiley Online Library
Impaired white matter integrity in traumatic brain injury (TBI) can lead to deficits in various
neurological functions. The differentiation of the underlying pathological processes, eg …

Investigating white matter tract microstructural changes at six–twelve weeks following mild traumatic brain injury: a combined diffusion tensor imaging and neurite …

LE Oehr, JYM Yang, J Chen, JJ Maller… - Journal of …, 2021 - liebertpub.com
Using diffusion-weighted imaging (DWI), research has demonstrated changes suggestive of
damage to white matter tracts (WMT) following mild traumatic brain injury (mTBI). Yet due to …