Objective: Because the extracellular matrix protein agrin is essential for neuromuscular
junction formation and maintenance, we tested the hypothesis that autoantibodies against …

To determine if patients with myasthenia gravis (MG) have antibodies to agrin, a
proteoglycan released by motor neurons and is critical for neuromuscular junction (NMJ) …

Myasthenia gravis (MG) is an autoimmune disorder of the neuromuscular junction (NMJ).
Most cases of MG are caused by autoantibodies against the acetylcholine receptor (AChR) …

Objectives To determine whether patients with myasthenia gravis (MG) have serum
antibodies to lipoprotein-related protein 4 (LRP4), a newly identified receptor for agrin that is …

Myasthenia gravis (MG) is an autoimmune disorder characterized by a defect in synaptic
transmission at the neuromuscular junction causing fluctuating muscle weakness with a …

Is “seronegative” MG explained by autoantibodies to MuSK? | Neurology Skip to main content
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In autoimmune myasthenia gravis (MG), the identification of antibodies and characterization
of serological subgroups is of great importance for diagnosis and management of the …

Introduction: The prevalence and characteristics of agrin and low‐density lipoprotein–
related receptor protein 4 (LRP4) antibody‐positive amyotrophic lateral sclerosis (ALS) …

Introduction Our aim in this study was to identify the prevalence and clinical characteristics of
LRP4/agrin‐antibody–positive double‐seronegative myasthenia gravis (DNMG). Methods …

Objective: Muscle-specific receptor tyrosine kinase (MuSK) antibody-positive myasthenia
gravis (MG) accounts for 5%–15% of autoimmune MG. MuSK mediates the agrin-signaling …