A vagal-NTS neural pathway that stimulates feeding

J Chen, M Cheng, L Wang, L Zhang, D Xu, P Cao… - Current Biology, 2020 - cell.com
A fundamental question of physiology is how gut-brain signaling stimulates appetite. While
many studies have emphasized the importance of vagal afferents to the brain in inducing …

Appetite signaling: from gut peptides and enteric nerves to brain

E Näslund, PM Hellström - Physiology & behavior, 2007 - Elsevier
The signaling systems underlying eating behavior control are complex. The current review
focuses on gastrointestinal (GI) signaling systems as physiological key functions for …

Central neurocircuits regulating food intake in response to gut inputs—preclinical evidence

KN Browning, KE Carson - Nutrients, 2021 - mdpi.com
The regulation of energy balance requires the complex integration of homeostatic and
hedonic pathways, but sensory inputs from the gastrointestinal (GI) tract are increasingly …

Genetically and functionally defined NTS to PBN brain circuits mediating anorexia

CW Roman, VA Derkach, RD Palmiter - Nature communications, 2016 - nature.com
The central nervous system controls food consumption to maintain metabolic homoeostasis.
In response to a meal, visceral signals from the gut activate neurons in the nucleus of the …

Dynamics of gut-brain communication underlying hunger

LR Beutler, Y Chen, JS Ahn, YC Lin, RA Essner… - Neuron, 2017 - cell.com
Communication between the gut and brain is critical for homeostasis, but how this
communication is represented in the dynamics of feeding circuits is unknown. Here we …

Proopiomelanocortin neurons in nucleus tractus solitarius are activated by visceral afferents: regulation by cholecystokinin and opioids

SM Appleyard, TW Bailey, MW Doyle… - Journal of …, 2005 - Soc Neuroscience
The nucleus tractus solitarius (NTS) receives dense terminations from cranial visceral
afferents, including those from the gastrointestinal (GI) system. Although the NTS integrates …

The gut–brain axis in health neuroscience: implications for functional gastrointestinal disorders and appetite regulation

N Weltens, J Iven, L Van Oudenhove… - Annals of the New York …, 2018 - Wiley Online Library
Over the past few years, scientific interest in the gut–brain axis (ie, the bidirectional
communication system between the gastrointestinal tract and the brain) has exploded …

[HTML][HTML] Vagus nerve stimulation increases stomach-brain coupling via a vagal afferent pathway

SJ Müller, V Teckentrup, I Rebollo, M Hallschmid… - Brain stimulation, 2022 - Elsevier
Background Maintaining energy homeostasis is vital and supported by vagal signaling
between digestive organs and the brain. Previous research has established a gastric …

Vagal sensory neurons and gut-brain signaling

DY Chuyue, QJ Xu, RB Chang - Current opinion in neurobiology, 2020 - Elsevier
Highlights• The vagus nerve is a crucial link between gut signals and the brain regulating
various functions such as energy homeostasis, digestion, immune responses, reward …

[HTML][HTML] Gut-brain communication by distinct sensory neurons differently controls feeding and glucose metabolism

D Borgmann, E Ciglieri, N Biglari, C Brandt, AL Cremer… - Cell metabolism, 2021 - cell.com
Sensory neurons relay gut-derived signals to the brain, yet the molecular and functional
organization of distinct populations remains unclear. Here, we employed intersectional …