A 14-year-old female with perinatally acquired HIV on boosted protease inhibitor (PI)
therapy with atazanavir and ritonavir rapidly developed cushingoid features with excessive …

Objective: To describe a case of Cushing syndrome in a child during concurrent use of
inhaled fluticasone propionate, nasal mometasone, and a highly active antiretroviral …

A 48-year-old woman with HIV infection developed Cushingoid features while she was
taking ritonavir-boosted darunavir. Cushing's syndrome was confirmed due to the drug …

We present 2 cases of Cushing syndrome with secondary adrenal insufficiency from
concomitant use of ritonavir and inhaled corticosteroids in children with human …

We should like to raise a few concerns. First, the study only included 19.8% of the whole
cohort. This may be partly because BP was only routinely measured in certain individuals …

Protease inhibitors boosted with ritonavir can lead to drug—drug interactions, particularly
with inhaled corticosteroids such as fluticasone, because of the potent inhibition of …

A36-year-old woman with HIV presented with recent weight gain, marked abdominal striae
and proximal muscle weakness. She had a four-year history of type 2 diabetes mellitus that …

Iatrogenic Cushing syndrome (CS) is a well-known complication of treating patients with
systemic steroids. More rarely, it has been described in HIV-positive patients on ritonavir …

In HIV-infected patients, ritonavir, a potent cytochrome P450 inhibitor, is increasingly used to
improve the pharmacokinetic profile of the associated protease inhibitor. HIV physicians are …

Background: Ritonavir, a potent inhibitor of CYP3A4 enzyme, can lead to high systemic
concentrations of fluticasone when these 2 drugs are coadministered. Exogenous Cushing …