MicroRNAs in B cell development and malignancy

TR Fernando, NI Rodriguez-Malave… - Journal of hematology & …, 2012 - Springer
MicroRNAs are small RNA molecules that regulate gene expression and play critical roles in
B cell development and malignancy. miRNA expression is important globally, as B cell …

The function of microRNAs in B-cell development, lymphoma, and their potential in clinical practice

B Zheng, Z Xi, R Liu, W Yin, Z Sui, B Ren… - Frontiers in …, 2018 - frontiersin.org
B-cell formation, development, and differentiation are complex processes regulated by
several mechanisms. Recently, there has been growing evidence indicating that microRNAs …

miRNAs in B cell development and lymphomagenesis

M Coffre, SB Koralov - Trends in molecular medicine, 2017 - cell.com
B lymphocytes are essential for an efficient immune response against a variety of
pathogens. A large fraction of hematologic malignancies is of B cell origin, suggesting that …

[HTML][HTML] MicroRNAs in B-cells: from normal differentiation to treatment of malignancies

SC Marques, MB Laursen, JS Bødker, MK Kjeldsen… - Oncotarget, 2015 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are small non-coding RNAs that play important post-transcriptional
regulatory roles in a wide range of biological processes. They are fundamental to the normal …

MicroRNAs in B-cell lymphomas: how a complex biology gets more complex

K Musilová, M Mráz - Leukemia, 2015 - nature.com
MicroRNAs (miRNAs) represent important regulators of gene expression besides
transcriptional control. miRNA regulation can be involved in the cell developmental fate …

miRNAs in B-cell lymphoma: Molecular mechanisms and biomarker potential

C Solé, E Larrea, G Di Pinto, M Tellaetxe, CH Lawrie - Cancer letters, 2017 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs that regulate many human genes
including those involved in normal B-cell development. When these miRNAs are aberrantly …

miRNAs in normal and malignant hematopoiesis

R Kotaki, R Koyama-Nasu, N Yamakawa… - International journal of …, 2017 - mdpi.com
Lineage specification is primarily regulated at the transcriptional level and lineage-specific
transcription factors determine cell fates. MicroRNAs (miRNAs) are 18–24 nucleotide-long …

MicroRNAs: Tiny regulators of gene expression with pivotal roles in normal B-Cell development and B-Cell chronic lymphocytic leukemia

K Katsaraki, P Karousi, PI Artemaki, A Scorilas… - Cancers, 2021 - mdpi.com
Simple Summary The involvement of miRNAs in physiological cellular processes has been
well documented. The development of B cells, which is dictated by a miRNA-transcription …

Small RNAs guide hematopoietic cell differentiation and function

F Navarro, J Lieberman - The Journal of Immunology, 2010 - journals.aai.org
MicroRNAs (miRNAs) are key regulators of gene expression that help direct normal
differentiation and malignant transformation of hematopoietic cells. This review summarizes …

The role of microRNAs in normal hematopoiesis and hematopoietic malignancies

J Kluiver, BJ Kroesen, S Poppema, A van den Berg - Leukemia, 2006 - nature.com
Over the past few years, it has become evident that microRNAs (miRNAs) play an important
regulatory role in various biological processes. Much effort has been put into the elucidation …