[HTML][HTML] Molecular Mechanisms of Hypoxic Responses via Unique Roles of Ras1, Cdc24 and Ptp3 in a Human Fungal Pathogen Cryptococcus neoformans

YC Chang, A Khanal Lamichhane, HM Garraffo… - PLoS …, 2014 - journals.plos.org
Cryptococcus neoformans encounters a low oxygen environment when it enters the human
host. Here, we show that the conserved Ras1 (a small GTPase) and Cdc24 (the guanine …

The RAM signaling pathway links morphology, thermotolerance, and CO2 tolerance in the global fungal pathogen Cryptococcus neoformans

BJ Chadwick, T Pham, X Xie, LC Ristow, DJ Krysan… - Elife, 2022 - elifesciences.org
The environmental pathogen Cryptococcus neoformans claims over 180,000 lives each
year. Survival of this basidiomycete at host CO2 concentrations has only recently been …

Ribonucleases and bacterial virulence

A Lawal, O Jejelowo, AK Chopra… - Microbial …, 2011 - Wiley Online Library
Bacterial stress responses provide them the opportunity to survive hostile environments,
proliferate and potentially cause diseases in humans and animals. The way in which …

The Second RNA Chaperone, Hfq2, Is Also Required for Survival under Stress and Full Virulence of Burkholderia cenocepacia J2315

CG Ramos, SA Sousa, AM Grilo… - Journal of …, 2011 - Am Soc Microbiol
Burkholderia cenocepacia J2315 is a highly virulent and epidemic clinical isolate of the B.
cepacia complex (Bcc), a group of bacteria that have emerged as important pathogens to …

Comparison of the RpoH-Dependent Regulon and General Stress Response in Neisseria gonorrhoeae

IC Gunesekere, CM Kahler, DR Powell… - Journal of …, 2006 - Am Soc Microbiol
In the gammaproteobacteria the RpoH regulon is often equated with the stress response, as
the regulon contains many of the genes that encode what have been termed heat shock …

[HTML][HTML] CtsR, the master regulator of stress-response in Oenococcus oeni, is a heat sensor interacting with ClpL1

M Darsonval, F Julliat, T Msadek, H Alexandre… - Frontiers in …, 2018 - frontiersin.org
Oenococcus oeni is a lactic acid bacterium responsible for malolactic fermentation of wine.
While many stress response mechanisms implemented by O. oeni during wine adaptation …

[HTML][HTML] Molecular Dissection of Crz1 and Its Dynamic Subcellular Localization in Cryptococcus neoformans

BJ Chadwick, BE Ross, X Lin - Journal of Fungi, 2023 - mdpi.com
Across lower eukaryotes, the transcription factor Crz1 is dephosphorylated by calcineurin,
which facilitates Crz1 translocation to the nucleus to regulate gene expression. In the fungal …

Targeted deletion of genes for eukaryotic RNA-binding proteins, Rbp1 and Rbp2, in the cyanobacterium Synechococcus sp. strain PCC7942: Rbp1 is indispensable …

C Sugita, M Mutsuda, M Sugiura… - FEMS microbiology …, 1999 - academic.oup.com
The unicellular cyanobacterium Synechococcus sp. strains PCC6301 and PCC7942 have
two homologous genes, rbp1 and rbp2, encoding small RNA-binding proteins, Rbp1 and …

MrpC, a CRP/Fnr homolog, functions as a negative autoregulator during the Myxococcus xanthus multicellular developmental program

M McLaughlin, V Bhardwaj, BE Feeley… - Molecular …, 2018 - Wiley Online Library
MrpC, a member of the CRP/Fnr superfamily of transcriptional regulators, plays a key role in
coordination of the multicellular developmental program in Myxococcus xanthus. Previous …

The RNA-binding protein ProQ impacts exopolysaccharide biosynthesis and second messenger cyclic di-GMP signaling in the fire blight pathogen Erwinia amylovora

X Yuan, LI Eldred, RR Kharadi, SM Slack… - Applied and …, 2022 - Am Soc Microbiol
Erwinia amylovora is a plant-pathogenic bacterium that causes fire blight disease in many
economically important plants, including apples and pears. This bacterium produces three …