Signaling of G protein-activated inwardly rectifying K+ (GIRK) channels is an important
mechanism of the parasympathetic regulation of the heart rate and cardiac excitability. GIRK …

G protein‐gated inwardly rectifying potassium (GIRK/Kir3) channels regulate cellular
excitability and neurotransmission. In this study, we used biochemical and morphological …

G-protein-coupled inwardly rectifying potassium channels (GIRK/Kir3. x) are involved in
neurotransmission-mediated reduction of excitability. The gating mechanism following G …

GIRK channels control spike frequency in atrial pacemaker cells and inhibitory potentials in
neurons. By directly responding to G proteins, PIP2 and Na+, GIRK is under the control of …

G protein activated K+ channels (GIRK, Kir3) are switched on by direct binding of Gβγ
following activation of Gi/o proteins via G protein‐coupled receptors (GPCRs). Although Gαi …

G protein-activated K+ channels (Kir3 or GIRK) are activated by direct interaction with Gβγ.
Gα is essential for specific signaling and regulates basal activity of GIRK (I basal) and …

G protein-activated inwardly rectifying potassium channel (GIRK) plays crucial roles in
regulating heart rate and neuronal excitability in eukaryotic cells. A variety of ligands …

G protein-coupled inward rectifier K+ (GIRK) channels regulate cellular excitability and
neurotransmission. The GIRK channels are activated by a number of inhibitory …

The cardiac G protein-gated K+ channel, I KACh, is activated by application of purified and
recombinant β and γ subunits (Gβγ) of heterotrimeric G proteins to excised inside-out …

G protein-gated inwardly rectifying potassium channels (GIRKs) are a family of homo-and
hetero-oligomeric K+ channels composed of different subunits (GIRK1 to 4 in mammals) …