Neuropsychiatric adverse effects of interferon-α: recognition and management
CL Raison, M Demetrashvili, L Capuron, AH Miller - CNS drugs, 2005 - Springer
Recombinant preparations of the cytokine interferon (IFN)-α are increasingly used to treat a
number of medical conditions, including chronic viral hepatitis and several malignancies …
number of medical conditions, including chronic viral hepatitis and several malignancies …
The phenomenology and treatment of interferon-induced depression
JM Loftis, P Hauser - Journal of affective disorders, 2004 - Elsevier
Interferon (IFN)-α, IFN-β, and IFN-γ are currently available for the treatment of malignancies,
viral infections (eg, hepatitis C virus), multiple sclerosis (MS), and skin conditions. In addition …
viral infections (eg, hepatitis C virus), multiple sclerosis (MS), and skin conditions. In addition …
Interferon-related depression: a primer on mechanisms, treatment, and prevention of a common clinical problem
E Franscina Pinto, C Andrade - Current neuropharmacology, 2016 - ingentaconnect.com
Background: Depression is among the commonest of psychiatric disorders, and
inflammatory mechanisms have been suggested to play a role in its pathophysiology …
inflammatory mechanisms have been suggested to play a role in its pathophysiology …
Psychopharmacological treatment of depression, anxiety, irritability and insomnia in patients receiving interferon-α: A prospective case series and a discussion of …
C Maddock, A Baita, MG Orrù, R Sitzia… - Journal of …, 2004 - journals.sagepub.com
We studied 60 patients receiving a 1-year course of interferon (IFN)-αtherapy for chronic
viral hepatitis. Patients underwent psychiatric assessment before starting the IFN-αtherapy …
viral hepatitis. Patients underwent psychiatric assessment before starting the IFN-αtherapy …
Major depression during interferon-α treatment: vulnerability and prevention
FE Lotrich - Dialogues in clinical neuroscience, 2009 - Taylor & Francis
Major Depressive Disorder (MDD) during interferons (IFN-α) treatment can occur within a
few months of therapy, and shares many homologies with other forms of MDD, Most patients …
few months of therapy, and shares many homologies with other forms of MDD, Most patients …
Interferon alpha (IFNα) and psychiatric syndromes: a review
M Schaefer, MA Engelbrechta, O Gut, BL Fiebich… - Progress in Neuro …, 2002 - Elsevier
Interferon alpha (IFNα) is used for the treatment of several disorders, such as chronic
hepatitis or malignant melanoma. During the therapy, IFNα may cause severe …
hepatitis or malignant melanoma. During the therapy, IFNα may cause severe …
Recurrence of depressive disorders after interferon-induced depression
Abstract Interferon alpha (IFN-α)-treated patients commonly develop depression during the
therapy period. Although most IFN-α-induced depressive disorders achieve remission after …
therapy period. Although most IFN-α-induced depressive disorders achieve remission after …
Neurotransmitter changes by interferon-alpha and therapeutic implications
M Schaefer, M Schwaiger, M Pich, K Lieb… - …, 2003 - thieme-connect.com
Interferon-alpha IFN-α) is a cytokine with strong antiviral and antiproliferative properties. IFN-
α is the only effective treatment for chronic hepatitis C and the first substance that shows …
α is the only effective treatment for chronic hepatitis C and the first substance that shows …
Interferon-alpha-induced depression: Comparisons between early-and late-onset subgroups and with patients with major depressive disorder
Abstract Interferon (IFN)-alpha, until recently the standard treatment of hepatitis C virus
(HCV) infection, is associated with a significant risk of major depressive episode (MDE, or …
(HCV) infection, is associated with a significant risk of major depressive episode (MDE, or …
Psychiatric side effects of interferon-β in multiple sclerosis
JL Goeb, C Even, G Nicolas, B Gohier, F Dubas… - European …, 2006 - cambridge.org
Psychiatric disorders, especially depression, are frequent in patients with multiple sclerosis
(MS). They are attributed both to the psychosocial impact of a chronic, usually progressive …
(MS). They are attributed both to the psychosocial impact of a chronic, usually progressive …