Identification of HLA-DR9 (DRB1∗ 0901)-binding peptide motifs using a phage fUSE5 random peptide library
S Fujisao, S Matsushita, T Nishi, Y Nishimura - Human immunology, 1996 - Elsevier
We identified HLA-DRB1∗ 0901-binding peptides by affinity-based selection of a phage
random peptide library using the biotinylated DR9 complex. Analogue peptides with single …
random peptide library using the biotinylated DR9 complex. Analogue peptides with single …
The impact of DR3 microvariation on peptide binding: The combinations of specific drβ residues critical to binding differ for different peptides
PE Posch, CK Hurley, A Geluk, THM Ottenhoff - Human immunology, 1996 - Elsevier
HLA-DR molecules are a group of highly polymorphic glycoprotein heterodimers that
present peptide antigens to T lymphocytes for immune surveillance. To assess the …
present peptide antigens to T lymphocytes for immune surveillance. To assess the …
HLA-DR3 molecules can bind peptides carrying two alternative specific submotifs.
A Geluk, KE van Meijgaarden… - … (Baltimore, Md.: 1950 …, 1994 - journals.aai.org
Three different HLA-DR3-specific peptide binding motifs have been proposed. These motifs
shared a major hydrophobic anchor at the N-terminus, but differed in the C-terminal anchor …
shared a major hydrophobic anchor at the N-terminus, but differed in the C-terminal anchor …
[HTML][HTML] Human leukocyte antigen (HLA)-DRB1* 15: 01 and HLA-DRB5* 01: 01 present complementary peptide repertoires
EM Scholz, M Marcilla, X Daura… - Frontiers in …, 2017 - frontiersin.org
Human leukocyte antigen (HLA)-DR15 is a haplotype associated with multiple sclerosis. It
contains the two DRB* genes DRB1* 1501 (DR2b) and DRB5* 0101 (DR2a). The reported …
contains the two DRB* genes DRB1* 1501 (DR2b) and DRB5* 0101 (DR2a). The reported …
Analysis of allele-specific contact sites of natural HLA-DR17 ligands.
G Malcherek, V Gnau, S Stevanovic… - … (Baltimore, Md.: 1950 …, 1994 - journals.aai.org
The sequence motif of peptide ligands naturally associated with DR17 has indicated
conserved residues at the relative positions P1-P4-P6-P 8.9 or 10. Eight naturally processed …
conserved residues at the relative positions P1-P4-P6-P 8.9 or 10. Eight naturally processed …
[引用][C] A distinctive peptide binding motif for HLA-DRB1 * 0407, an HLA-DR4 subtype not associated with rheumatoid arthritis
MP Davenport, A Godkin, T Friede, S Stevanović… - Immunogenetics, 1997 - Springer
Several HLA alleles have been associated with susceptibility to rheumatoid arthritis. In
particular HLA-DRB1* 0401,* 0404 and* 0405 (HLA-DR4 Dw4, Dw14 and Dw15) have been …
particular HLA-DRB1* 0401,* 0404 and* 0405 (HLA-DR4 Dw4, Dw14 and Dw15) have been …
HLA-DRβ chain residues that are predicted to be located in the floor of the peptide-binding groove contribute to antibody-binding epitopes
E Klohe, X Fu, M Ballas, RW Karr - Human immunology, 1993 - Elsevier
The purpose of this study was to identify polymorphic residues in HLA-DRβ chains that are
involved in the epitopes recognized by DRw52-like mAbs. Flow cytometric analysis of …
involved in the epitopes recognized by DRw52-like mAbs. Flow cytometric analysis of …
Definition of the peptide binding motif within DRB1* 1401 restricted epitopes by peptide competition and structural modeling
EA James, AK Moustakas, DA Berger, L Huston… - Molecular …, 2008 - Elsevier
This study identified the peptide-binding motif of HLA-DRA/DRB1* 1401 (DR1401). First,
peptides containing DR1401 restricted epitopes were identified using tetramer-guided …
peptides containing DR1401 restricted epitopes were identified using tetramer-guided …
Several common HLA-DR types share largely overlapping peptide binding repertoires
S Southwood, J Sidney, A Kondo… - The Journal of …, 1998 - journals.aai.org
The peptide binding specificities of HLA-DRB1* 0401, DRB1* 0101, and DRB1* 0701 have
been analyzed by the use of large collections of synthetic peptides corresponding to …
been analyzed by the use of large collections of synthetic peptides corresponding to …
Different regions of the N-terminal domains of HLA-DR1 influence recognition of individual peptide-DR1 complexes
L Tuosto, RW Karr, XT Fu, RR Olson, E Cundari… - Human immunology, 1994 - Elsevier
The contributions of individual amino acids in the polymorphic β chain and the conserved α
chain of HLA-DR1 to influenza HA-specific DR1-restricted and anti-DR1 allospecific T-cell …
chain of HLA-DR1 to influenza HA-specific DR1-restricted and anti-DR1 allospecific T-cell …