Natural sesquiterpene quinone/quinols: chemistry, biological activity, and synthesis

XH Tian, LL Hong, WH Jiao, HW Lin - Natural Product Reports, 2023 - pubs.rsc.org
Covering: 2010 to 2021 Sesquiterpene quinone/quinols (SQs) are characterized by a C15-
sesquiterpenoid unit incorporating a C6-benzoquinone/quinol moiety. Numerous …

Progress in the total synthesis of epoxyquinone natural products: An update

G Mehta, S Sengupta - Tetrahedron, 2017 - Elsevier
Epoxyquinone natural products continue to attract the attention of organic synthesis
community worldwide, owing to their increasingly diverse and complex molecular …

Yicathins B and C and analogues: Total synthesis, lipophilicity and biological activities

DRP Loureiro, ÁF Magalhães, JX Soares… - …, 2020 - Wiley Online Library
Natural products have always been an important source of new hits and leads in drug
discovery, with the marine environment being regarded as a significant source of novel and …

Arylcyanomethylenequinone oximes: An overview of synthesis, chemical transformations, and biological activity

K Kula, R Nagatsky, M Sadowski, Y Siumka… - Molecules, 2023 - mdpi.com
Quinone methides are a class of biologically active compounds that can be used in
medicine as antibacterial, antifungal, antiviral, antioxidant, and anti-inflammatory agents. In …

Natural diterpene and triterpene quinone methides: Structures, synthesis and biological potentials

Q Zhou - Quinone Methides, 2009 - Wiley Online Library
Quinone methides (QMs) are reactive intermediates that have been involved in the covalent
modification of biomolecules such as DNA and proteins to impact related biological events …

Therapeutic significance of quinolines: a patent review (2013-2015)

SMA Hussaini - Expert opinion on therapeutic patents, 2016 - Taylor & Francis
Introduction: Quinoline is a versatile bicyclic heterocyclic scaffold with immense therapeutic
potential. Some of the compounds containing quinoline nucleus are agents of choice for the …

Quinoline‐derivatives as privileged scaffolds for medicinal and pharmaceutical chemists: A comprehensive review

V Yadav, J Reang, V Sharma, J Majeed… - Chemical Biology & …, 2022 - Wiley Online Library
The quinoline scaffolds are privileged for their numerous biological activities in the
pharmaceutical field. This moiety constitutes a well‐known space in several marketed …

Quinolizidine-type alkaloids: chemodiversity, occurrence, and bioactivity

W Cely-Veloza, MJ Kato, E Coy-Barrera - ACS omega, 2023 - ACS Publications
Quinolizidine alkaloids (QAs) are nitrogen-containing compounds produced naturally as
specialized metabolites distributed in plants and animals (eg, frogs, sponges). The present …

Chalcone scaffolds, bioprecursors of flavonoids: Chemistry, bioactivities, and pharmacokinetics

M Rudrapal, J Khan, AAB Dukhyil, RMII Alarousy… - Molecules, 2021 - mdpi.com
Chalcones are secondary metabolites belonging to the flavonoid (C6-C3-C6 system) family
that are ubiquitous in edible and medicinal plants, and they are bioprecursors of plant …

Current progress toward synthetic routes and medicinal significance of quinoline

WS Shehab, MMK Amer, DA Elsayed, KK Yadav… - Medicinal Chemistry …, 2023 - Springer
Quinoline motifs are essential in several pharmacological active heterocyclic compounds
due to their various applications in medicinal and industrial chemistry. Furthermore, there …