[HTML][HTML] Development and validation of LC-MS/MS method for determination of cytisine in human serum and saliva
Cytisine (CYT) is a quinolizidine alkaloid used for nicotine addiction treatment. Recent
clinical trial data regarding cytisine confirm its high effectiveness and safety as a smoking …
clinical trial data regarding cytisine confirm its high effectiveness and safety as a smoking …
[HTML][HTML] Comparison of various chromatographic systems for analysis of cytisine in human serum, saliva and pharmaceutical formulation by HPLC with diode array …
K Wróblewski, A Petruczynik, T Tuzimski, D Przygodzka… - Molecules, 2019 - mdpi.com
Background: Identification and quantitative determination of cytisine, especially in biological
samples and pharmaceutical formulations, is still a difficult analytical task. Cytisine is an …
samples and pharmaceutical formulations, is still a difficult analytical task. Cytisine is an …
Plasma concentrations of cytisine, a commercially available plant-based alkaloid, in healthy adult smokers taking recommended doses for smoking cessation
SH Jeong, J Sheridan, D Newcombe, M Tingle - Xenobiotica, 2018 - Taylor & Francis
Cytisine is a plant alkaloid that is a partial agonist for the α4β2-nAChRs and is used as an
aid to smoking cessation. To date, there are no published data on cytisine concentrations in …
aid to smoking cessation. To date, there are no published data on cytisine concentrations in …
Cytisine for nicotine addiction treatment: a review of pharmacology, therapeutics and an update of clinical trial evidence for smoking cessation
P Tutka, D Vinnikov, RJ Courtney, NL Benowitz - Addiction, 2019 - Wiley Online Library
Aims To review cytisine's history of use, pre‐clinical evidence, clinical pharmacokinetics,
efficacy, adverse reactions (ARs) and safety for smoking cessation. Methods A synoptic …
efficacy, adverse reactions (ARs) and safety for smoking cessation. Methods A synoptic …
Pharmacokinetics of cytisine, an α4β2 nicotinic receptor partial agonist, in healthy smokers following a single dose
SH Jeong, D Newcombe, J Sheridan… - Drug testing and …, 2015 - Wiley Online Library
Cytisine, an α4β2 nicotinic receptor partial agonist, is a plant alkaloid that is commercially
extracted for use as a smoking cessation medication. Despite its long history of use, there is …
extracted for use as a smoking cessation medication. Despite its long history of use, there is …
[HTML][HTML] Cytisine: state of the art in pharmacological activities and pharmacokinetics
X Wang, J Yang, P Huang, D Wang, Z Zhang… - Biomedicine & …, 2024 - Elsevier
Cytisine is a naturally occurring bioactive compound, an alkaloid mainly isolated from
legume plants. In recent years, various biological activities of cytisine have been explored …
legume plants. In recent years, various biological activities of cytisine have been explored …
[PDF][PDF] Pharmacokinetics of cytisine after single intravenous and oral administration in rabbits
H Astroug, R Simeonova, L Kassabova… - Interdisciplinary …, 2010 - sciendo.com
The aim of this study is to develop a sensitive HPLC method for the quantitative
determination of cytisine in serum and to characterize the pharmacokinetic behaviour of …
determination of cytisine in serum and to characterize the pharmacokinetic behaviour of …
[PDF][PDF] Cytisine for the treatment of nicotine addiction: from a molecule to therapeutic efficacy
P Tutka, W Zatoñski - Pharmacological reports, 2006 - Citeseer
Cytisine, a natural plant alkaloid, has been marketed in Central and Eastern Europe for over
40 years for the clinical management of smoking cessation. Despite the fact that cytisine has …
40 years for the clinical management of smoking cessation. Despite the fact that cytisine has …
A phase I, double-blind, randomized, placebo-controlled, single dose-escalation study to evaluate the tolerability, and safety of cytisinicline in adult smokers
C Jacobs, M Fonseca, NA Rigotti… - Nicotine and …, 2023 - academic.oup.com
Introduction Cytisinicline is a nicotinic acetylcholine receptor partial agonist marketed
historically as oral tablets in Central and Eastern Europe as an aid to smoking cessation …
historically as oral tablets in Central and Eastern Europe as an aid to smoking cessation …
Cytisine—from ethomedical use to the development as a natural alternative for smoking cessation
V Tzankova, N Danchev - Biotechnology & Biotechnological …, 2007 - Taylor & Francis
Cigarette smoking is the one of the prevalent risk factors for morbidity in the world. The
treatment of smoking is rapidly changing. Alternative approaches to the nicotine …
treatment of smoking is rapidly changing. Alternative approaches to the nicotine …
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