Con: can comparing adherent to non-adherent patients provide useful estimates of the effect of continuous positive airway pressure?
SR Patel, AM Sawyer, DJ Gottlieb - Sleep, 2024 - academic.oup.com
The recently published technology assessment of continuous positive airway pressure
(CPAP), prepared by the Agency for Healthcare Research and Quality (AHRQ) and entitled …
(CPAP), prepared by the Agency for Healthcare Research and Quality (AHRQ) and entitled …
Pro: comparing adherent to non-adherent patients can provide useful estimates of the effect of continuous positive airway pressure on cardiovascular outcomes
Whether or not there are cardiovascular benefits of using continuous positive airway
pressure (CPAP) for patients with obstructive sleep apnea (OSA) is a foundational question …
pressure (CPAP) for patients with obstructive sleep apnea (OSA) is a foundational question …
Strategies to assess the effect of continuous positive airway pressure on long-term clinically important outcomes among patients with symptomatic obstructive sleep …
LM Donovan, CM Hoyos, RJ Kimoff… - Annals of the …, 2023 - atsjournals.org
Continuous positive airway pressure (CPAP) is the first-line treatment for obstructive sleep
apnea (OSA). Although CPAP improves symptoms (eg, daytime sleepiness), there is a lack …
apnea (OSA). Although CPAP improves symptoms (eg, daytime sleepiness), there is a lack …
Continuous positive airway pressure and adverse cardiovascular events in obstructive sleep apnea: are participants of randomized trials representative of sleep clinic …
A Reynor, N McArdle, B Shenoy, SS Dhaliwal, SC Rea… - Sleep, 2022 - academic.oup.com
Abstract Study Objectives Randomized controlled trials (RCTs) have shown no reduction in
adverse cardiovascular (CV) events in patients randomized to continuous positive airway …
adverse cardiovascular (CV) events in patients randomized to continuous positive airway …
Where to next for optimizing adherence in large-scale trials of continuous positive airway pressure?
AM Sawyer, DM Wallace, LF Buenaver… - Sleep medicine …, 2021 - sleep.theclinics.com
Clinical trials are defined as experiments in humans designed to evaluate the effects of
specific treatments, or exposure condition that by design reduce random error and bias. 1 …
specific treatments, or exposure condition that by design reduce random error and bias. 1 …
Obstructive sleep apnea: the elephant in the cardiovascular room
JP Bakker, B Sharma, A Malhotra - Chest, 2012 - journal.chestnet.org
Despite considerable advances in the relatively young field of sleep research, the
importance of obstructive sleep apnea (OSA) remains underappreciated. A vast body of …
importance of obstructive sleep apnea (OSA) remains underappreciated. A vast body of …
Continuous positive airway pressure adherence for prevention of major adverse cerebrovascular and cardiovascular events in obstructive sleep apnea
S Javaheri, MA Martinez-Garcia… - American journal of …, 2020 - atsjournals.org
Obstructive sleep apnea (OSA) is associated with major adverse cerebrovascular and
cardiovascular events (MACCEs)(1). Multiple studies have demonstrated the beneficial …
cardiovascular events (MACCEs)(1). Multiple studies have demonstrated the beneficial …
CPAP therapy for obstructive sleep apnoea: are the right questions being asked?
DJ Gottlieb - European Respiratory Journal, 2023 - Eur Respiratory Soc
Extract The recently published technology assessment of continuous positive airway
pressure (CPAP), prepared for the Agency for Healthcare Research and Quality (AHRQ) of …
pressure (CPAP), prepared for the Agency for Healthcare Research and Quality (AHRQ) of …
[PDF][PDF] Cardiovascular events in obstructive sleep apnea-can CPAP therapy SAVE lives
B Mokhlesi, NT Ayas - N Engl J Med, 2016 - pulmcast.com
Obstructive sleep apnea is a common disorder that has been associated with an increased
risk of cardiovascular disease. 1 Continuous positive airway pressure (CPAP) is frequently …
risk of cardiovascular disease. 1 Continuous positive airway pressure (CPAP) is frequently …
Randomized clinical trials of cardiovascular disease in obstructive sleep apnea: understanding and overcoming bias
RD McEvoy, M Sánchez-de-la-Torre, Y Peker… - Sleep, 2021 - academic.oup.com
In their recent provocative commentary, Pack et al.[1] contend that the neutral results of
randomized controlled trials (RCTs) of continuous positive airways pressure (CPAP) for …
randomized controlled trials (RCTs) of continuous positive airways pressure (CPAP) for …