Effect of dietary factors and time of day on iron absorption from oral iron supplements in iron deficient women

HK von Siebenthal, D Moretti… - American Journal of …, 2023 - Wiley Online Library
Guidelines generally recommend taking iron supplements in the morning away from meals
and with ascorbic acid (AA) to increase iron absorption. However, there is little direct …

Oral iron supplements increase hepcidin and decrease iron absorption from daily or twice-daily doses in iron-depleted young women

D Moretti, JS Goede, C Zeder, M Jiskra… - Blood, The Journal …, 2015 - ashpublications.org
Iron supplements acutely increase hepcidin, but the duration and magnitude of the increase,
its dose dependence, and its effects on subsequent iron absorption have not been …

[HTML][HTML] Iron absorption from supplements is greater with alternate day than with consecutive day dosing in iron-deficient anemic women

NU Stoffel, C Zeder, GM Brittenham, D Moretti… - …, 2020 - ncbi.nlm.nih.gov
In iron-depleted women without anemia, oral iron supplements induce an increase in serum
hepcidin (SHep) that persists for 24 hours, decreasing iron absorption from supplements …

Iron absorption from oral iron supplements given on consecutive versus alternate days and as single morning doses versus twice-daily split dosing in iron-depleted …

NU Stoffel, CI Cercamondi, G Brittenham… - The Lancet …, 2017 - thelancet.com
Background Current guidelines to treat iron deficiency recommend daily provision of ferrous
iron divided through the day to increase absorption. However, daily dosing and split dosing …

The role of oral iron in the treatment of adults with iron deficiency

JO Lo, AE Benson, KL Martens… - European Journal of …, 2023 - Wiley Online Library
Iron deficiency is the most common nutrient deficiency in the world, affecting over 20% of
premenopausal women worldwide. Oral iron supplementation is often the first‐line treatment …

[HTML][HTML] Oral iron supplementation in iron-deficient women: How much and how often?

NU Stoffel, HK von Siebenthal, D Moretti… - Molecular aspects of …, 2020 - Elsevier
Iron deficiency and iron deficiency anemia (IDA) are major public health problems
worldwide, especially in young women. Oral iron supplementation can be an effective …

[HTML][HTML] Serum iron curves can be used to estimate dietary iron bioavailability in humans

RE Conway, CA Geissler, RC Hider… - The Journal of …, 2006 - Elsevier
Erythrocyte incorporation of isotopic iron (Fe) is the standard method for assessing iron
bioavailability, but the process is expensive, technically difficult, and gives no information on …

Estimates of total body iron indicate 19 mg and 38 mg oral iron are equivalent for the mitigation of iron deficiency in individuals experiencing repeated phlebotomy

W Bialkowski, JE Kiss, DJ Wright… - American journal of …, 2017 - Wiley Online Library
Iron deficiency anemia is a common clinical condition often treated with tablets containing
65 mg of elemental iron. Such doses can elicit gastrointestinal side effects lowering patient …

[HTML][HTML] Iron absorption in young Indian women: the interaction of iron status with the influence of tea and ascorbic acid

P Thankachan, T Walczyk, S Muthayya… - The American journal of …, 2008 - Elsevier
Background Ascorbic acid (AA) enhances and tea inhibits iron absorption. It is unclear
whether iron status influences the magnitude of this effect. Objective We evaluated the …

Randomized controlled trial of twice-daily versus alternate-day oral iron therapy in the treatment of iron-deficiency anemia

R Kaundal, P Bhatia, A Jain, A Jain… - Annals of …, 2020 - Springer
Recent studies in iron-depleted women have challenged the current approach of treating
iron-deficiency anemia (IDA) with oral iron in divided daily doses. Alternate day dosing leads …