Cytomegalovirus

PD Griffiths, VC Emery, R Milne - Clinical virology, 2009 - Wiley Online Library
Human cytomegalovirus (HCMV) was first isolated 50 years ago, when the new technology
of cell culture became available. The pathogenesis of HCMV disease is complex, involving …

The pathogenicity of human cytomegalovirus: an overview

ES Huang, TF Kowalik - Molecular aspects of human cytomegalovirus …, 1993 - Springer
Defining causality between an agent-be it a virus, bacteria, or chemical—and a disease is
the principal aim of biomedical research. Achievement of this lofty goal is hampered when …

The pathogenesis of human cytomegalovirus

P Griffiths, I Baraniak, M Reeves - The Journal of pathology, 2015 - Wiley Online Library
Human cytomegalovirus (HCMV) is a recognized cause of disease in the fetus, the allograft
recipient and AIDS patients. More recently, it has been recognized as a pathogen for those …

Nonradioactive PCR-enzyme-linked immunosorbent assay method for detection of human cytomegalovirus DNA

RD Allen, PE Pellett, JA Stewart… - Journal of clinical …, 1995 - Am Soc Microbiol
We developed a rapid, sensitive, and specific PCR-based assay for human cytomegalovirus
(HCMV). The assay includes primer and probe sequences derived from conserved HCMV …

Guinea pig cytomegalovirus gene expression

HC Isom, CY Yin - Cytomegaloviruses, 1990 - Springer
Human cytomegalovirus (HCMV) is a significant human pathogen and its clinical importance
has recently become more predominantly recognized because of the severity of HCMV …

Diagnosis of human cytomegalovirus infection: laboratory approaches

ES Huang, TF Kowalik - Molecular Aspects of Human Cytomegalovirus …, 1993 - Springer
The association of cytomegalovirus (CMV) with a plethora of diseases and the recent
development of potent anti-CMV compounds warrants the need for accurate verification of …

Human cytomegalovirus: pathogenesis and models of latency

J Sinclair, JGP Sissons - Seminars in Virology, 1994 - Elsevier
As with all herpesviruses, human cytomegalovirus (HCMV) can establish lifelong
persistence after primary infection, with reactivation occurring often as a result of …

Human cytomegalovirus and immunopathology

JGP Sissons, AJ Carmichael… - Seminars in …, 2002 - search.proquest.com
Human cytomegalovirus (HCMV) is a ubiquitous human persistent virus, which causes
disease particularly in the setting of immunosuppression. This review deals with aspects of …

Pathogenesis of human cytomegalovirus in the immunocompromised host

P Griffiths, M Reeves - Nature Reviews Microbiology, 2021 - nature.com
Human cytomegalovirus (HCMV) is a herpesvirus that infects~ 60% of adults in developed
countries and more than 90% in developing countries. Usually, it is controlled by a vigorous …

[图书][B] Human cytomegalovirus

TE Shenk, MF Stinski - 2008 - Springer
The earliest observation of cytomegalovirus (CMV) interactions with the host cell was owl
eye cytopathology in various tissues. It was recognized in the early 1970s that human CMV …