A new essential protein discovery method based on the integration of protein-protein interaction and gene expression data
Background Identification of essential proteins is always a challenging task since it requires
experimental approaches that are time-consuming and laborious. With the advances in high …
experimental approaches that are time-consuming and laborious. With the advances in high …
A new method for the discovery of essential proteins
Background Experimental methods for the identification of essential proteins are always
costly, time-consuming, and laborious. It is a challenging task to find protein essentiality only …
costly, time-consuming, and laborious. It is a challenging task to find protein essentiality only …
Effective identification of essential proteins based on priori knowledge, network topology and gene expressions
Identification of essential proteins is very important for understanding the minimal
requirements for cellular life and also necessary for a series of practical applications, such …
requirements for cellular life and also necessary for a series of practical applications, such …
Identification of essential proteins based on edge clustering coefficient
Identification of essential proteins is key to understanding the minimal requirements for
cellular life and important for drug design. The rapid increase of available protein-protein …
cellular life and important for drug design. The rapid increase of available protein-protein …
Prediction of essential proteins based on overlapping essential modules
Many computational methods have been proposed to identify essential proteins by using the
topological features of interactome networks. However, the precision of essential protein …
topological features of interactome networks. However, the precision of essential protein …
A topology potential-based method for identifying essential proteins from PPI networks
Essential proteins are indispensable for cellular life. It is of great significance to identify
essential proteins that can help us understand the minimal requirements for cellular life and …
essential proteins that can help us understand the minimal requirements for cellular life and …
A local average connectivity-based method for identifying essential proteins from the network level
Identifying essential proteins is very important for understanding the minimal requirements of
cellular survival and development. Fast growth in the amount of available protein–protein …
cellular survival and development. Fast growth in the amount of available protein–protein …
A novel essential protein identification method based on PPI networks and gene expression data
J Zhong, C Tang, W Peng, M Xie, Y Sun, Q Tang… - BMC …, 2021 - Springer
Background Some proposed methods for identifying essential proteins have better results by
using biological information. Gene expression data is generally used to identify essential …
using biological information. Gene expression data is generally used to identify essential …
UDoNC: an algorithm for identifying essential proteins based on protein domains and protein-protein interaction networks
Prediction of essential proteins which are crucial to an organism's survival is important for
disease analysis and drug design, as well as the understanding of cellular life. The majority …
disease analysis and drug design, as well as the understanding of cellular life. The majority …
Random walk based method to identify essential proteins by integrating network topology and biological characteristics
Essential proteins are regarded as the fundamental components of living organisms. The
identification of essential proteins greatly contributes to the understanding of cellular …
identification of essential proteins greatly contributes to the understanding of cellular …