Analysis of the clinico-hematological relevance of the breakpoint location within M-BCR in chronic myeloid leukemia
A Bennour, I Ouahchi, B Achour, M Zaier, YB Youssef… - Medical oncology, 2013 - Springer
Abstract The Philadelphia chromosome (Ph) derives from the balanced translocation
between chromosomes 9 and 22. This chromosomal translocation results in the fusion …
between chromosomes 9 and 22. This chromosomal translocation results in the fusion …
Mapping of breakpoints, and relationship to BCR-ABL RNA expression, in Philadelphia-chromosome-positive chronic myeloid leukaemia patients with a breakpoint …
KI Mills, AM Sproul, D Leibowitz, AK Burnett - Leukemia, 1991 - europepmc.org
The BCR gene, on chromosome 22, is involved in the Philadelphia (Ph1) chromosome
which is a characteristic cytogenetic marker of chronic myeloid leukaemia (CML) …
which is a characteristic cytogenetic marker of chronic myeloid leukaemia (CML) …
Relationship of the BCR gene breakpoint and the type of BCR/ABL transcript to clinical course, prognostic indexes and survival in patients with chronic myeloid …
W Prejzner - Medical science monitor, 2002 - medscimonit.com
BACKGROUND: Chronic myeloid leukemia is characterized by the presence ofthe
Philadelphia chromosome. At the molecular level a fusion of part of the ABL and BCR genes …
Philadelphia chromosome. At the molecular level a fusion of part of the ABL and BCR genes …
[HTML][HTML] New type of Bcr/Abl junction in Philadelphia chromosome-positive chronic myelogenous leukemia
G Saglio, A Guerrasio, C Rosso, A Zaccaria… - Blood, 1990 - Elsevier
A new and rare type of Bcr/Abl junction between exon C3 of the 3'portion of the Bcr gene
and Abl exon 2 has been identified in the leukemic cells of two Ph 1-positive chronic …
and Abl exon 2 has been identified in the leukemic cells of two Ph 1-positive chronic …
Clinical impact of breakpoint position within M-bcr in chronic myeloid leukemia.
T Fioretos, PG Nilsson, P Aman, S Heim… - Leukemia, 1993 - europepmc.org
We have analyzed the M-bcr breakpoint position in 133 Philadelphia-positive chronic
myeloid leukemia patients and correlated the findings with clinical, hematologic, and …
myeloid leukemia patients and correlated the findings with clinical, hematologic, and …
The first BCR gene intron contains breakpoints in Philadelphla chromosome positive leukemia
N Heisterkamp, E Knoppel, J Groffen - Nucleic acids research, 1988 - academic.oup.com
The hallmark of chronic myelogenous leukemia (CML) is a translocation between
chromosomes 9 and 22-the Philadelphia (Ph') translocation. The translocation is also found …
chromosomes 9 and 22-the Philadelphia (Ph') translocation. The translocation is also found …
No correlation between locations of bcr breakpoints and clinical states in Ph1-positive CML patients.
H Ogawa, H Sugiyama, T Soma, T Masaoka… - Leukemia, 1989 - europepmc.org
The majority of patients with chronic myelogenous leukemia (CML) have a characteristic
reciprocal translocation between chromosome 9 and 22, resulting in the Philadelphia (Ph1) …
reciprocal translocation between chromosome 9 and 22, resulting in the Philadelphia (Ph1) …
[引用][C] No correlation between the type of bcr-abl hybrid messenger RNA and platelet counts in chronic myelogenous leukemia
B Opalka, UB Wandl, R Stutenkemper, O Kloke… - 1992 - ashpublications.org
The consistent genetic marker of chronic myelogenous leukemia (CML) is the Philadelphia
translocation t (9; 22), resulting in formation of a hybrid bcr-ab1 gene and expression of the …
translocation t (9; 22), resulting in formation of a hybrid bcr-ab1 gene and expression of the …
A polymorphism in exon b2 of the major breakpoint cluster region (M‐bcr) identified in chronic myeloid leukaemia patients
RDV Meissner, PMB Dias, DT Covas… - British journal of …, 1998 - Wiley Online Library
The BCR/ABL junctional region and the b3 exon from chronic myeloid leukaemia (CML)
patients were sequenced. In all 21 samples analysed the junctional region, as well as the b3 …
patients were sequenced. In all 21 samples analysed the junctional region, as well as the b3 …
Analysis of the clinical relevance of the breakpoint location within M-BCR and the type of chimeric mRNA in chronic myelogenous leukemia.
C Rozman, A Urbano-Ispizua, F Cervantes, M Rozman… - Leukemia, 1995 - europepmc.org
It has been suggested that the breakpoint location within the M-BCR segment of
chromosome 22 and the type of chimeric mRNA BCR/ABL (b2a2 or b3a2) are associated …
chromosome 22 and the type of chimeric mRNA BCR/ABL (b2a2 or b3a2) are associated …