Obesity and cancer: inflammation bridges the two
R Kolb, FS Sutterwala, W Zhang - Current opinion in pharmacology, 2016 - Elsevier
Highlights•Obesity is associated with chronic inflammation and chronic diseases.•Obesity is
associated with increased risk and progression of several cancers.•The mechanism by …
associated with increased risk and progression of several cancers.•The mechanism by …
Obesity, inflammation, and cancer
Obesity, a worldwide epidemic, confers increased risk for multiple serious conditions,
including cancer, and is increasingly recognized as a growing cause of preventable cancer …
including cancer, and is increasingly recognized as a growing cause of preventable cancer …
Obesity and cancer: local and systemic mechanisms
NM Iyengar, CA Hudis… - Annual review of …, 2015 - annualreviews.org
Obesity is a leading modifiable risk factor for the development of several epithelial
malignancies. In addition to increasing risk, obesity also confers worse prognosis for many …
malignancies. In addition to increasing risk, obesity also confers worse prognosis for many …
The growing challenge of obesity and cancer: an inflammatory issue
AE Harvey, LM Lashinger… - Annals of the New York …, 2011 - Wiley Online Library
The prevalence of obesity, an established risk factor for many cancers, has risen steadily for
the past several decades in the United States and in many parts of the world. This review …
the past several decades in the United States and in many parts of the world. This review …
Obesity, metabolic dysregulation, and cancer: a growing concern and an inflammatory (and microenvironmental) issue
SD Hursting, SM Dunlap - Annals of the New York Academy of …, 2012 - Wiley Online Library
Obesity is an established risk and progression factor for many cancers. In the United States
more than one‐third of adults, and nearly one in five children, are currently obese. Thus, a …
more than one‐third of adults, and nearly one in five children, are currently obese. Thus, a …
Association of obesity-related metabolic disruptions with cancer risk and outcome
AE Lohmann, PJ Goodwin, RT Chlebowski… - Journal of Clinical …, 2016 - ascopubs.org
Over the past 40 years, the prevalence of obesity has increased epidemically worldwide,
which raises significant concerns regarding public health and the associated economic …
which raises significant concerns regarding public health and the associated economic …
Targeting obesity-related dysfunction in hormonally driven cancers
Obesity is a risk factor for at least 13 different types of cancer, many of which are hormonally
driven, and is associated with increased cancer incidence and morbidity. Adult obesity rates …
driven, and is associated with increased cancer incidence and morbidity. Adult obesity rates …
Obesity and cancer mechanisms: tumor microenvironment and inflammation
NM Iyengar, A Gucalp, AJ Dannenberg… - Journal of clinical …, 2016 - ascopubs.org
Purpose There is growing evidence that inflammation is a central and reversible mechanism
through which obesity promotes cancer risk and progression. Methods We review recent …
through which obesity promotes cancer risk and progression. Methods We review recent …
Signals from the adipose microenvironment and the obesity–cancer link—a systematic review
Obesity and its associated metabolic dysregulation are established risk factors for many
cancers. However, the biologic mechanisms underlying this relationship remain …
cancers. However, the biologic mechanisms underlying this relationship remain …
Obesity: A perfect storm for carcinogenesis
BHL Harris, VM Macaulay, DA Harris… - Cancer and Metastasis …, 2022 - Springer
Obesity-related cancers account for 40% of the cancer cases observed in the USA and
obesity is overtaking smoking as the most widespread modifiable risk factor for …
obesity is overtaking smoking as the most widespread modifiable risk factor for …