Quantitative detection and prognostic value of antibodies against M-type phospholipase A2 receptor and its cysteine-rich ricin domain and C-type lectin domains 1 …

X Liu, J Xue, T Li, Q Wu, H Sheng, X Yang, B Lin… - Plos one, 2024 - journals.plos.org
Background M-type phospholipase A2 receptor (PLA2R) is the major autoantigen in adult
idiopathic membranous nephropathy (IMN). Although reactive epitopes in the PLA2R …

[HTML][HTML] Idiopathic membranous nephropathy and anti-phospholipase A2 receptor antibodies

A Nayer, A Asif - Journal of nephropathology, 2013 - ncbi.nlm.nih.gov
Membranous nephropathy (MN) is a glomerular disease due to subepithelial immune
deposits and local complement activation resulting in podocyte injury and proteinuria …

Refining our understanding of the PLA2R-antibody response in primary membranous nephropathy: looking forward, looking back

LH Beck Jr, DJ Salant - Journal of the American Society of …, 2020 - journals.lww.com
Since the M-type phospholipase A2 receptor (PLA2R) was described as the major
autoantigen in membranous nephropathy (MN) a decade ago, many studies have advanced …

Immunohistochemical glomerular expression of phospholipase A2 receptor in primary and secondary membranous nephropathy: A retrospective study in an Indian …

S Roy, A Korula, G Basu, S Jacob, S Varughese… - Nephron Extra, 2017 - karger.com
Background: Limited published literature exists on the utility and standardization of anti-
phospholipase A2 receptor (anti-PLA2R) immunohistochemistry (IHC) for the diagnosis of …

HLA-DRB1* 15: 01 and HLA-DRB3* 02: 02 in PLA2R-related membranous nephropathy

WB Le, JS Shi, T Zhang, L Liu, HZ Qin… - Journal of the …, 2017 - journals.lww.com
Idiopathic membranous nephropathy (MN) is associated with HLA; however, the HLA allele
involved remains unknown. To identify the HLA risk alleles associated with phospholipase …

HLA alleles and prognosis of PLA2R-related membranous nephropathy

WB Le, JS Shi, Y Fan, SW Gong - Clinical Journal of the American …, 2021 - journals.lww.com
Results A total of 79 HLA alleles were identified in this study. Four HLA alleles, DRB1* 13:
01 (n= 12; hazard ratio, 3.7; 95% confidence interval, 1.8 to 7.8; P< 0.001), DQB1* 06: 03 (n …

PLA2R Antibody Levels and Clinical Outcome in Patients with Membranous Nephropathy and Non-Nephrotic Range Proteinuria under Treatment with Inhibitors of …

E Hoxha, S Harendza, H Pinnschmidt, U Panzer… - PloS one, 2014 - journals.plos.org
Patients with primary membranous nephropathy (MN) who experience spontaneous
remission of proteinuria generally have an excellent outcome without need of …

Clinical value of a serum anti-PLA2R antibody in the diagnosis and monitoring of primary membranous nephropathy in adults

X Wu, L Liu, Y Guo, L Yang - International journal of nephrology …, 2018 - Taylor & Francis
Objective To compare the positive rate of anti-PLA2R antibodies in patients with primary
membranous nephropathy (PMN), secondary membranous nephropathy (SMN), and non …

[HTML][HTML] A new chemiluminescence immunoassay for phospholipase A2 receptor 1 autoantibodies allows early identification of autoantibody recurrence in patients …

E Hoxha, RAK Stahl, L Reinhard, A Kühnl… - Kidney International …, 2021 - Elsevier
Background Circulating autoantibodies against the M-type phospholipase A 2 receptor 1
(PLA 2 R1) are important biomarkers in membranous nephropathy (MN), supporting the …

A cohort study of membranous nephropathy, primary or secondary

M Arghiani, BH Zamani, F Nazemian, S Samadi… - BMC nephrology, 2021 - Springer
Abstract Background Although IgG4 deposit against phospholipase A2 receptor (anti-
PLA2R) is predominantly presented in the renal biopsy of patients with primary membranous …