[HTML][HTML] Epithelial to mesenchymal transition as a biomarker in renal fibrosis: are we ready for the bedside?

P Galichon, A Hertig - Fibrogenesis & tissue repair, 2011 - Springer
Over the past two decades, the concept of the epithelial to mesenchymal transition (EMT)
has been imported from embryology and oncology to fibrosis, particularly in the kidney. This …

EMT–MET in renal disease: Should we curb our enthusiasm?

P Galichon, S Finianos, A Hertig - Cancer letters, 2013 - Elsevier
Renal epithelial cells arise during embryogenesis by mesenchymal to epithelial transition
(MET). In the context of renal diseases, these cells can switch back to a mesenchymal …

[HTML][HTML] Epithelial-mesenchymal transition (EMT) in kidney fibrosis: fact or fantasy?

W Kriz, B Kaissling, M Le Hir - The Journal of clinical …, 2011 - Am Soc Clin Investig
Epithelial-mesenchymal transition (EMT) has become widely accepted as a mechanism by
which injured renal tubular cells transform into mesenchymal cells that contribute to the …

[HTML][HTML] Scar wars: mapping the fate of epithelial–mesenchymal–myofibroblast transition

SE Quaggin, A Kapus - Kidney international, 2011 - Elsevier
The hypothesis that epithelial–mesenchymal transition (EMT) might be a contributor to the
accumulation of fibroblasts and myofibroblasts (MFs) in the kidney during fibrogenesis was …

[HTML][HTML] New insights into the role and mechanism of partial epithelial-mesenchymal transition in kidney fibrosis

L Sheng, S Zhuang - Frontiers in physiology, 2020 - frontiersin.org
Epithelial-mesenchymal transition (EMT) is described as the process in which injured renal
tubular epithelial cells undergo a phenotype change, acquiring mesenchymal characteristics …

Epithelial to mesenchymal transition (EMT) and endothelial to mesenchymal transition (EndMT): role and implications in kidney fibrosis

AS Cruz-Solbes, K Youker - Kidney development and disease, 2017 - Springer
Tubulointerstitial injury is one of the hallmarks of renal disease. In particular, interstitial
fibrosis has a prominent role in the development and progression of kidney injury. Collagen …

[PDF][PDF] Fibroblasts emerge via epithelial-mesenchymal transition in chronic kidney fibrosis

M Zeisberg, R Kalluri - Front Biosci, 2008 - article.imrpress.com
[Frontiers in Bioscience 13, 6991-6998, May 1, 2008] 6991 Fibroblasts emerge via epithelial-mesenchymal
transition in chronic ki Page 1 [Frontiers in Bioscience 13, 6991-6998, May 1, 2008] 6991 …

[HTML][HTML] Epithelial-mesenchymal transition and its implications for fibrosis

R Kalluri, EG Neilson - The Journal of clinical investigation, 2003 - Am Soc Clin Investig
Epithelial to mesenchymal transition (EMT) is a central mechanism for diversifying the cells
found in complex tissues. This dynamic process helps organize the formation of the body …

Epithelial‐mesenchymal transition in renal fibrosis–evidence for and against

M Fragiadaki, RM Mason - International journal of experimental …, 2011 - Wiley Online Library
Epithelial to mesenchymal transition (EMT) is a well established biological process in
metazoan embryological development. Over the past 15 years, investigators have sought to …

Epithelial to mesenchymal transition in renal fibrogenesis: pathologic significance, molecular mechanism, and therapeutic intervention

Y Liu - Journal of the American Society of Nephrology, 2004 - journals.lww.com
Mature tubular epithelial cells in adult kidney can undergo epithelial-to-mesenchymal
transition (EMT), a phenotypic conversion that is fundamentally linked to the pathogenesis of …